Cargando…
The gp130/STAT3-endoplasmic reticulum stress axis regulates hepatocyte necroptosis in acute liver injury
AIM: To investigate the effect of the gp130/STAT3-endoplasmic reticulum (ER) stress axis on hepatocyte necroptosis during acute liver injury. METHODS: ER stress and liver injury in LO2 cells were induced with thapsigargin, and in BALB/c mice with tunicamycin and carbon tetrachloride (CCl(4)). Glycop...
Autores principales: | Li, Xia, Wang, Jie, Li, Ying, He, Wei, Cheng, Qi-Jiao, Liu, Xia, Xu, De-Lin, Jiang, Zhi-Gang, Xiao, Xue, He, Yi-Huai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Croatian Medical Schools
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332293/ https://www.ncbi.nlm.nih.gov/pubmed/37391912 http://dx.doi.org/10.3325/cmj.2023.64.149 |
Ejemplares similares
-
Intracellular alpha-fetoprotein mitigates hepatocyte apoptosis and necroptosis by inhibiting endoplasmic reticulum stress
por: Chen, Yun-Fen, et al.
Publicado: (2022) -
Feedback loop between hepatocyte nuclear factor 1α and endoplasmic reticulum stress mitigates liver injury by downregulating hepatocyte apoptosis
por: Liu, Si-Ying, et al.
Publicado: (2022) -
Hepatocyte Specific gp130 Signalling Underlies APAP Induced Liver Injury
por: Dong, Jinrui, et al.
Publicado: (2022) -
Targeting the gp130/STAT3 Axis Attenuates Tumor Microenvironment Mediated Chemoresistance in Group 3 Medulloblastoma Cells
por: Sreenivasan, Lakshana, et al.
Publicado: (2022) -
Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model
por: Hatting, M, et al.
Publicado: (2015)