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Myxedema Coma: A Grave Phenomenon Partially Reversed CKD Status With Treatment of Hypothyroidism

Myxedema coma is a grave medical condition that warrants emergent medical management to avoid adverse effects and unfavorable outcomes. Intravenous thyroid hormones (T3 and T4), along with intravenous hydrocortisone and frequent vital monitoring, are the mainstays of the management of myxedema coma....

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Autores principales: Mandyam, Saikiran, Valisekka, Sai Sudha, Parghi, Devam, Chirrareddy, Yagnapriya, Kalluru, Pavan Kumar Reddy, Ibie, Nowoghomwenma C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332427/
https://www.ncbi.nlm.nih.gov/pubmed/37435271
http://dx.doi.org/10.7759/cureus.40221
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author Mandyam, Saikiran
Valisekka, Sai Sudha
Parghi, Devam
Chirrareddy, Yagnapriya
Kalluru, Pavan Kumar Reddy
Ibie, Nowoghomwenma C
author_facet Mandyam, Saikiran
Valisekka, Sai Sudha
Parghi, Devam
Chirrareddy, Yagnapriya
Kalluru, Pavan Kumar Reddy
Ibie, Nowoghomwenma C
author_sort Mandyam, Saikiran
collection PubMed
description Myxedema coma is a grave medical condition that warrants emergent medical management to avoid adverse effects and unfavorable outcomes. Intravenous thyroid hormones (T3 and T4), along with intravenous hydrocortisone and frequent vital monitoring, are the mainstays of the management of myxedema coma. The interplay between CKD and hypothyroidism is fascinating and can affect each other. It is often very difficult for physicians to differentiate between sepsis and myxedema coma, especially in the early stages. Infections and medication non-compliance are the leading causes of precipitation myxedema coma. We describe a case report presented with myxedema coma and CKD, which was successfully managed and also led to a partial reversal of CKD status. 
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spelling pubmed-103324272023-07-11 Myxedema Coma: A Grave Phenomenon Partially Reversed CKD Status With Treatment of Hypothyroidism Mandyam, Saikiran Valisekka, Sai Sudha Parghi, Devam Chirrareddy, Yagnapriya Kalluru, Pavan Kumar Reddy Ibie, Nowoghomwenma C Cureus Endocrinology/Diabetes/Metabolism Myxedema coma is a grave medical condition that warrants emergent medical management to avoid adverse effects and unfavorable outcomes. Intravenous thyroid hormones (T3 and T4), along with intravenous hydrocortisone and frequent vital monitoring, are the mainstays of the management of myxedema coma. The interplay between CKD and hypothyroidism is fascinating and can affect each other. It is often very difficult for physicians to differentiate between sepsis and myxedema coma, especially in the early stages. Infections and medication non-compliance are the leading causes of precipitation myxedema coma. We describe a case report presented with myxedema coma and CKD, which was successfully managed and also led to a partial reversal of CKD status.  Cureus 2023-06-10 /pmc/articles/PMC10332427/ /pubmed/37435271 http://dx.doi.org/10.7759/cureus.40221 Text en Copyright © 2023, Mandyam et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Mandyam, Saikiran
Valisekka, Sai Sudha
Parghi, Devam
Chirrareddy, Yagnapriya
Kalluru, Pavan Kumar Reddy
Ibie, Nowoghomwenma C
Myxedema Coma: A Grave Phenomenon Partially Reversed CKD Status With Treatment of Hypothyroidism
title Myxedema Coma: A Grave Phenomenon Partially Reversed CKD Status With Treatment of Hypothyroidism
title_full Myxedema Coma: A Grave Phenomenon Partially Reversed CKD Status With Treatment of Hypothyroidism
title_fullStr Myxedema Coma: A Grave Phenomenon Partially Reversed CKD Status With Treatment of Hypothyroidism
title_full_unstemmed Myxedema Coma: A Grave Phenomenon Partially Reversed CKD Status With Treatment of Hypothyroidism
title_short Myxedema Coma: A Grave Phenomenon Partially Reversed CKD Status With Treatment of Hypothyroidism
title_sort myxedema coma: a grave phenomenon partially reversed ckd status with treatment of hypothyroidism
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332427/
https://www.ncbi.nlm.nih.gov/pubmed/37435271
http://dx.doi.org/10.7759/cureus.40221
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