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Unique Variant of Zieve Syndrome With a Normal Reticulocyte Count
Zieve syndrome is a rare diagnosis seen in patients with chronic alcohol use which consists of a distinct clinical triad of hyperlipidemia, hemolytic anemia, and jaundice. Patients typically have an elevated reticulocyte count due to the hemolytic nature of the anemia. We present the case of a 44-ye...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elmer Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332873/ https://www.ncbi.nlm.nih.gov/pubmed/37435106 http://dx.doi.org/10.14740/jmc4077 |
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author | Vedire, Apurva Imburgio, Steven Sanekommu, Harshavardhan Patel, Rushi Johnson, Haley Taj, Sobaan Hossain, Mohammad |
author_facet | Vedire, Apurva Imburgio, Steven Sanekommu, Harshavardhan Patel, Rushi Johnson, Haley Taj, Sobaan Hossain, Mohammad |
author_sort | Vedire, Apurva |
collection | PubMed |
description | Zieve syndrome is a rare diagnosis seen in patients with chronic alcohol use which consists of a distinct clinical triad of hyperlipidemia, hemolytic anemia, and jaundice. Patients typically have an elevated reticulocyte count due to the hemolytic nature of the anemia. We present the case of a 44-year-old female who was discovered to have an unusual variant of Zieve syndrome with a normal reticulocyte count, which was believed to be due to suppression of bone marrow from excessive alcohol consumption. She was treated with steroids and complete alcohol cessation, with remarkable improvement on subsequent follow-up. An exhaustive literature review of 31 documented cases of Zieve syndrome was conducted to better understand the clinical presentation and overall prognosis of these patients. This case report and literature review aimed to improve patient outcomes through increased recognition of this underrecognized syndrome. |
format | Online Article Text |
id | pubmed-10332873 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elmer Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-103328732023-07-11 Unique Variant of Zieve Syndrome With a Normal Reticulocyte Count Vedire, Apurva Imburgio, Steven Sanekommu, Harshavardhan Patel, Rushi Johnson, Haley Taj, Sobaan Hossain, Mohammad J Med Cases Case Report Zieve syndrome is a rare diagnosis seen in patients with chronic alcohol use which consists of a distinct clinical triad of hyperlipidemia, hemolytic anemia, and jaundice. Patients typically have an elevated reticulocyte count due to the hemolytic nature of the anemia. We present the case of a 44-year-old female who was discovered to have an unusual variant of Zieve syndrome with a normal reticulocyte count, which was believed to be due to suppression of bone marrow from excessive alcohol consumption. She was treated with steroids and complete alcohol cessation, with remarkable improvement on subsequent follow-up. An exhaustive literature review of 31 documented cases of Zieve syndrome was conducted to better understand the clinical presentation and overall prognosis of these patients. This case report and literature review aimed to improve patient outcomes through increased recognition of this underrecognized syndrome. Elmer Press 2023-06 2023-06-29 /pmc/articles/PMC10332873/ /pubmed/37435106 http://dx.doi.org/10.14740/jmc4077 Text en Copyright 2023, Vedire et al. https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Vedire, Apurva Imburgio, Steven Sanekommu, Harshavardhan Patel, Rushi Johnson, Haley Taj, Sobaan Hossain, Mohammad Unique Variant of Zieve Syndrome With a Normal Reticulocyte Count |
title | Unique Variant of Zieve Syndrome With a Normal Reticulocyte Count |
title_full | Unique Variant of Zieve Syndrome With a Normal Reticulocyte Count |
title_fullStr | Unique Variant of Zieve Syndrome With a Normal Reticulocyte Count |
title_full_unstemmed | Unique Variant of Zieve Syndrome With a Normal Reticulocyte Count |
title_short | Unique Variant of Zieve Syndrome With a Normal Reticulocyte Count |
title_sort | unique variant of zieve syndrome with a normal reticulocyte count |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332873/ https://www.ncbi.nlm.nih.gov/pubmed/37435106 http://dx.doi.org/10.14740/jmc4077 |
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