Severe Hepatitis-associated Aplastic Anemia Following COVID-19 mRNA Vaccination

We herein report a case of hepatitis-associated aplastic anemia (HAAA) that occurred after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. In this patient, progressive pancytopenia observed two months after acute hepatitis following the second dose of the SARS-CoV-2 vaccine...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamamoto, Michio, Keino, Dai, Sumii, Shinichiro, Yokosuka, Tomoko, Goto, Hiroaki, Inui, Ayano, Sogo, Tsuyoshi, Kawakami, Makio, Tanaka, Mio, Yanagimachi, Masakatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332982/
https://www.ncbi.nlm.nih.gov/pubmed/36948624
http://dx.doi.org/10.2169/internalmedicine.1308-22
_version_ 1785070554514980864
author Yamamoto, Michio
Keino, Dai
Sumii, Shinichiro
Yokosuka, Tomoko
Goto, Hiroaki
Inui, Ayano
Sogo, Tsuyoshi
Kawakami, Makio
Tanaka, Mio
Yanagimachi, Masakatsu
author_facet Yamamoto, Michio
Keino, Dai
Sumii, Shinichiro
Yokosuka, Tomoko
Goto, Hiroaki
Inui, Ayano
Sogo, Tsuyoshi
Kawakami, Makio
Tanaka, Mio
Yanagimachi, Masakatsu
author_sort Yamamoto, Michio
collection PubMed
description We herein report a case of hepatitis-associated aplastic anemia (HAAA) that occurred after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. In this patient, progressive pancytopenia observed two months after acute hepatitis following the second dose of the SARS-CoV-2 vaccine indicated the development of HAAA. Although some reports have suggested that SARS-CoV-2 vaccination may be involved in the development of autoimmune diseases, no cases of HAAA developing after SARS-CoV-2 vaccination have been reported. SARS-CoV-2 vaccination in children has only started relatively recently, so the range of side effects in children has not yet been thoroughly described. Therefore, we need to strengthen surveillance for symptoms of children who are vaccinated.
format Online
Article
Text
id pubmed-10332982
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher The Japanese Society of Internal Medicine
record_format MEDLINE/PubMed
spelling pubmed-103329822023-07-12 Severe Hepatitis-associated Aplastic Anemia Following COVID-19 mRNA Vaccination Yamamoto, Michio Keino, Dai Sumii, Shinichiro Yokosuka, Tomoko Goto, Hiroaki Inui, Ayano Sogo, Tsuyoshi Kawakami, Makio Tanaka, Mio Yanagimachi, Masakatsu Intern Med Case Report We herein report a case of hepatitis-associated aplastic anemia (HAAA) that occurred after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. In this patient, progressive pancytopenia observed two months after acute hepatitis following the second dose of the SARS-CoV-2 vaccine indicated the development of HAAA. Although some reports have suggested that SARS-CoV-2 vaccination may be involved in the development of autoimmune diseases, no cases of HAAA developing after SARS-CoV-2 vaccination have been reported. SARS-CoV-2 vaccination in children has only started relatively recently, so the range of side effects in children has not yet been thoroughly described. Therefore, we need to strengthen surveillance for symptoms of children who are vaccinated. The Japanese Society of Internal Medicine 2023-03-22 2023-06-15 /pmc/articles/PMC10332982/ /pubmed/36948624 http://dx.doi.org/10.2169/internalmedicine.1308-22 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Yamamoto, Michio
Keino, Dai
Sumii, Shinichiro
Yokosuka, Tomoko
Goto, Hiroaki
Inui, Ayano
Sogo, Tsuyoshi
Kawakami, Makio
Tanaka, Mio
Yanagimachi, Masakatsu
Severe Hepatitis-associated Aplastic Anemia Following COVID-19 mRNA Vaccination
title Severe Hepatitis-associated Aplastic Anemia Following COVID-19 mRNA Vaccination
title_full Severe Hepatitis-associated Aplastic Anemia Following COVID-19 mRNA Vaccination
title_fullStr Severe Hepatitis-associated Aplastic Anemia Following COVID-19 mRNA Vaccination
title_full_unstemmed Severe Hepatitis-associated Aplastic Anemia Following COVID-19 mRNA Vaccination
title_short Severe Hepatitis-associated Aplastic Anemia Following COVID-19 mRNA Vaccination
title_sort severe hepatitis-associated aplastic anemia following covid-19 mrna vaccination
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332982/
https://www.ncbi.nlm.nih.gov/pubmed/36948624
http://dx.doi.org/10.2169/internalmedicine.1308-22
work_keys_str_mv AT yamamotomichio severehepatitisassociatedaplasticanemiafollowingcovid19mrnavaccination
AT keinodai severehepatitisassociatedaplasticanemiafollowingcovid19mrnavaccination
AT sumiishinichiro severehepatitisassociatedaplasticanemiafollowingcovid19mrnavaccination
AT yokosukatomoko severehepatitisassociatedaplasticanemiafollowingcovid19mrnavaccination
AT gotohiroaki severehepatitisassociatedaplasticanemiafollowingcovid19mrnavaccination
AT inuiayano severehepatitisassociatedaplasticanemiafollowingcovid19mrnavaccination
AT sogotsuyoshi severehepatitisassociatedaplasticanemiafollowingcovid19mrnavaccination
AT kawakamimakio severehepatitisassociatedaplasticanemiafollowingcovid19mrnavaccination
AT tanakamio severehepatitisassociatedaplasticanemiafollowingcovid19mrnavaccination
AT yanagimachimasakatsu severehepatitisassociatedaplasticanemiafollowingcovid19mrnavaccination

Ejemplares similares