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Macrophages play a leading role in determining the direction of astrocytic migration in spinal cord injury via ADP-P2Y1R axis

After spinal cord injury (SCI), inflammatory cells such as macrophages infiltrate the injured area, and astrocytes migrate, forming a glial scar around macrophages. The glial scar inhibits axonal regeneration, resulting in significant permanent disability. However, the mechanism through which glial...

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Detalles Bibliográficos
Autores principales: Ono, Gentaro, Kobayakawa, Kazu, Saiwai, Hirokazu, Tamaru, Tetsuya, Iura, Hirotaka, Haruta, Yohei, Kitade, Kazuki, Iida, Keiichiro, Kawaguchi, Kenichi, Matsumoto, Yoshihiro, Tsuda, Makoto, Tamura, Tomohiko, Ozato, Keiko, Inoue, Kazuhide, Konno, Dai-Jiro, Maeda, Takeshi, Okada, Seiji, Nakashima, Yasuharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333181/
https://www.ncbi.nlm.nih.gov/pubmed/37429920
http://dx.doi.org/10.1038/s41598-023-38301-8