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Combined multidimensional single-cell protein and RNA profiling dissects the cellular and functional heterogeneity of thymic epithelial cells

The network of thymic stromal cells provides essential niches with unique molecular cues controlling T cell development and selection. Recent single-cell RNA sequencing studies have uncovered previously unappreciated transcriptional heterogeneity among thymic epithelial cells (TEC). However, there a...

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Detalles Bibliográficos
Autores principales: Klein, Fabian, Veiga-Villauriz, Clara, Börsch, Anastasiya, Maio, Stefano, Palmer, Sam, Dhalla, Fatima, Handel, Adam E., Zuklys, Saulius, Calvo-Asensio, Irene, Musette, Lucas, Deadman, Mary E., White, Andrea J., Lucas, Beth, Anderson, Graham, Holländer, Georg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333192/
https://www.ncbi.nlm.nih.gov/pubmed/37429879
http://dx.doi.org/10.1038/s41467-023-39722-9