Cargando…

Microglia and cognitive impairment in schizophrenia: translating scientific progress into novel therapeutic interventions

Cognitive impairment is a core clinical feature of schizophrenia, exerting profound adverse effects on social functioning and quality of life in a large proportion of patients with schizophrenia. However, the mechanisms underlying the pathogenesis of schizophrenia-related cognitive impairment are no...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhuo, Chuanjun, Tian, Hongjun, Song, Xueqin, Jiang, Deguo, Chen, Guangdong, Cai, Ziyao, Ping, Jing, Cheng, Langlang, Zhou, Chunhua, Chen, Chunmian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333203/ https://www.ncbi.nlm.nih.gov/pubmed/37429882 http://dx.doi.org/10.1038/s41537-023-00370-z

Ejemplares similares

Associations of cognitive impairment in patients with schizophrenia with genetic features and with schizophrenia-related structural and functional brain changes
por: Zhuo, Chuanjun, et al.
Publicado: (2022)

Low-dose lithium adjunct to atypical antipsychotic treatment nearly improved cognitive impairment, deteriorated the gray-matter volume, and decreased the interleukin-6 level in drug-naive patients with first schizophrenia symptoms: a follow-up pilot study
por: Zhuo, Chuanjun, et al.
Publicado: (2023)

Lithium produces bi-directionally regulation of mood disturbance, acts synergistically with anti-depressive/-manic agents, and did not deteriorate the cognitive impairment in murine model of bipolar disorder
por: Zhuo, Chuanjun, et al.
Publicado: (2022)

Brain Neural Activity Patterns in an Animal Model of Antidepressant-Induced Manic Episodes
por: Chen, Min, et al.
Publicado: (2022)

Validity and reliability of a Chinese version of the self‐evaluation of negative symptoms
por: Chen, Guangdong, et al.
Publicado: (2023)

Aberrant patterns of local and long-range functional connectivity densities in schizophrenia
por: Liu, Chuanxin, et al.
Publicado: (2017)

Metabolic risk factors of cognitive impairment in young women with major psychiatric disorder
por: Zhuo, Chuanjun, et al.
Publicado: (2022)

Irreversible Primary Visual Cortex Impairment in a Mouse Model of High-Risk Schizophrenia
por: Chen, Xinying, et al.
Publicado: (2021)

Validation of a modified Chinese‐language version of the Davos Assessment of Cognitive Biases Scale (MCL‐DACOBS) in a sample of Chinese patients with schizophrenia
por: Chen, Guangdong, et al.
Publicado: (2023)

Validation and reliability test of Chinese language patient-reported impact of symptoms in schizophrenia scale
por: Lin, Xiao, et al.
Publicado: (2023)

Testing the validity and reliability of the Chinese version of the Staden schizophrenia anxiety rating scale
por: Du, Chenyuan, et al.
Publicado: (2022)

Transcranial direct current stimulation of the occipital lobes with adjunct lithium attenuates the progression of cognitive impairment in patients with first episode schizophrenia
por: Zhuo, Chuanjun, et al.
Publicado: (2022)

Calcium imaging reveals depressive- and manic-phase-specific brain neural activity patterns in a murine model of bipolar disorder: a pilot study
por: Chen, Min, et al.
Publicado: (2021)

Strategies to solve the reverse inference fallacy in future MRI studies of schizophrenia: a review
por: Zhuo, Chuanjun, et al.
Publicado: (2020)

Acid sphingomyelinase/ceramide system in schizophrenia: implications for therapeutic intervention as a potential novel target
por: Zhuo, Chuanjun, et al.
Publicado: (2022)

Impact of aerobic exercise on cognitive function in patients with schizophrenia during daily nursing: A protocol for systematic review and meta-analysis
por: Chen, Chunmian, et al.
Publicado: (2021)

Baseline global brain structural and functional alterations at the time of symptom onset can predict subsequent cognitive deterioration in drug-naïve first-episode schizophrenia patients: Evidence from a follow-up study
por: Zhuo, Chuanjun, et al.
Publicado: (2022)

Polymorphisms in Dopaminergic Genes in Schizophrenia and Their Implications in Motor Deficits and Antipsychotic Treatment
por: Ye, Jiaen, et al.
Publicado: (2019)

Risk-to-befit ratios of consecutive antidepressants for heavy menstrual bleeding in young women with bipolar disorder or major depressive disorder
por: Zhuo, Chuanjun, et al.
Publicado: (2022)

Validity and reliability of a Chinese version of the Bergen Work Addiction Scale
por: Liu, Yuanyuan, et al.
Publicado: (2023)

A borderline personality assessment for adolescents: Validity and reliability of the Chinese languages borderline personality features scale (short form version) for adolescents/children
por: Zhuo, Chuanjun, et al.
Publicado: (2022)

Prevalence of Heavy Menstrual Bleeding and Its Associated Cognitive Risks and Predictive Factors in Women With Severe Mental Disorders
por: Shan, Jianmin, et al.
Publicado: (2022)

Abberant inverted U-shaped brain pattern and trait-related retinal impairment in schizophrenia patients with combined auditory and visual hallucinations: a pilot study
por: Zhuo, Chuanjun, et al.
Publicado: (2020)

Efficacy and Tolerability of Second and Third Generation Anti-epileptic Drugs in Refractory Epilepsy: A Network Meta-Analysis
por: Zhuo, Chuanjun, et al.
Publicado: (2017)

Lithium bidirectionally regulates depression- and mania-related brain functional alterations without worsening cognitive function in patients with bipolar disorder
por: Zhuo, Chuanjun, et al.
Publicado: (2022)

A unified model of shared brain structural alterations in patients with different mental disorders who experience own‐thought auditory verbal hallucinations—A pilot study
por: Zhuo, Chuanjun, et al.
Publicado: (2020)

The rise and fall of MRI studies in major depressive disorder
por: Zhuo, Chuanjun, et al.
Publicado: (2019)

Without insight accompanied with deteriorated brain functional alterations in healthy individuals with auditory verbal hallucinations: a pilot study
por: Zhuo, Chuanjun, et al.
Publicado: (2019)

Exploration of the cortical pathophysiology underlying visual disturbances in schizophrenia comorbid with depressive disorder—An evidence from mouse model
por: Liu, Jian, et al.
Publicado: (2021)

Pseudo-continuous arterial spin labeling imaging of cerebral blood perfusion asymmetry in drug-naïve patients with first-episode major depression
por: Chen, Guangdong, et al.
Publicado: (2016)

Double-Edged Sword of Tumour Suppressor Genes in Schizophrenia
por: Zhuo, Chuanjun, et al.
Publicado: (2019)

Transient effects of multi‐infusion ketamine augmentation on treatment‐resistant depressive symptoms in patients with treatment‐resistant bipolar depression – An open‐label three‐week pilot study
por: Zhuo, Chuanjun, et al.
Publicado: (2020)

Metformin Enhances Antidepressant/Antipsychotic Combination Therapy of Schizophrenia With Comorbid Depression in a Murine Model
por: Zhou, Chunhua, et al.
Publicado: (2020)

Antipsychotic agents deteriorate brain and retinal function in schizophrenia patients with combined auditory and visual hallucinations: A pilot study and secondary follow‐up study
por: Zhuo, Chuanjun, et al.
Publicado: (2020)

Anxiety and clinical outcomes of patients with acute coronary syndrome: a meta-analysis
por: Li, Jie, et al.
Publicado: (2020)

Lower risk of liver cancer in patients with schizophrenia: a systematic review and meta-analysis of cohort studies
por: Xu, Dali, et al.
Publicado: (2017)

Effects of ketamine on circadian rhythm and synaptic homeostasis in patients with treatment‐resistant depression: A protocol for mechanistic studies of its rapid and sustained antidepressant actions in humans
por: Zhuo, Chuanjun, et al.
Publicado: (2019)

Adjunct ketamine treatment of depression in treatment‐resistant schizophrenia patients is unsatisfactory in pilot and secondary follow‐up studies
por: Zhuo, Chuanjun, et al.
Publicado: (2020)

Diffusion Tensor MR Imaging Evaluation of Callosal Abnormalities in Schizophrenia: A Meta-Analysis
por: Zhuo, Chuanjun, et al.
Publicado: (2016)

Lipidomics of the brain, retina, and biofluids: from the biological landscape to potential clinical application in schizophrenia
por: Zhuo, Chuanjun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_akf06ki8eo6bofbrf91ceqjrui