Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer’s disease

Neurogenesis, crucial for brain resilience, is reduced in Alzheimer’s disease (AD) that induces astroglial reactivity at the expense of the pro-neurogenic potential, and restoring neurogenesis could counteract neurodegenerative pathology. However, the molecular mechanisms promoting pro-neurogenic as...

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Detalles Bibliográficos
Autores principales: Siddiqui, Tohid, Cosacak, Mehmet Ilyas, Popova, Stanislava, Bhattarai, Prabesh, Yilmaz, Elanur, Lee, Annie J., Min, Yuhao, Wang, Xue, Allen, Mariet, İş, Özkan, Atasavum, Zeynep Tansu, Rodriguez-Muela, Natalia, Vardarajan, Badri N., Flaherty, Delaney, Teich, Andrew F., Santa-Maria, Ismael, Freudenberg, Uwe, Werner, Carsten, Tosto, Giuseppe, Mayeux, Richard, Ertekin-Taner, Nilüfer, Kizil, Caghan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333226/
https://www.ncbi.nlm.nih.gov/pubmed/37429840
http://dx.doi.org/10.1038/s41536-023-00311-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333226/
https://www.ncbi.nlm.nih.gov/pubmed/37429840
http://dx.doi.org/10.1038/s41536-023-00311-5

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