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Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1

Scribble (Scrib) is a multidomain polarity protein and member of the leucine-rich repeat and PDZ domain (LAP) protein family. A loss of Scrib expression is associated with disturbed apical-basal polarity and tumor formation. The tumor-suppressive activity of Scrib correlates with its membrane locali...

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Detalles Bibliográficos
Autores principales: Thüring, Eva-Maria, Hartmann, Christian, Maddumage, Janesha C., Javorsky, Airah, Michels, Birgitta E., Gerke, Volker, Banks, Lawrence, Humbert, Patrick O., Kvansakul, Marc, Ebnet, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333293/
https://www.ncbi.nlm.nih.gov/pubmed/37430142
http://dx.doi.org/10.1038/s42003-023-05088-3