Altered Distribution of SNARE Proteins in Primary Neurons Exposed to Different Alpha-Synuclein Proteoforms

Growing evidence indicates that the pathological alpha-synuclein (α-syn) aggregation in Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) starts at the synapses. Physiologic α-syn is involved in regulating neurotransmitter release by binding to the SNARE complex protein VAMP-2 on synaptic...

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Detalles Bibliográficos
Autores principales: Brolin, Emma, Ingelsson, Martin, Bergström, Joakim, Erlandsson, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333399/
https://www.ncbi.nlm.nih.gov/pubmed/37130995
http://dx.doi.org/10.1007/s10571-023-01355-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333399/
https://www.ncbi.nlm.nih.gov/pubmed/37130995
http://dx.doi.org/10.1007/s10571-023-01355-3

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