Cargando…

Structural, harmonic force field and vibrational studies of cholinesterase inhibitor tacrine used for treatment of Alzheimer's disease

Different structures of free base (FB), two cationic forms (CA) and three hydrochloride forms (HCl) of cholinesterase inhibitor tacrine used for treatment of Alzheimer ’s disease was evaluated using hybrid B3LYP calculations in order to perform their complete vibrational assignments using the scaled...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sundius, Tom, Brandán, Silvia Antonia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333470/ https://www.ncbi.nlm.nih.gov/pubmed/37441405 http://dx.doi.org/10.1016/j.heliyon.2023.e17280

Ejemplares similares

Structural and vibrational characterization of di-hydrated hydrochloride tacrine combining DFT with SQMFF approach
por: Sundius, Tom, et al.
Publicado: (2023)

Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors
por: Svobodova, Barbora, et al.
Publicado: (2019)

A combined study on structures and vibrational spectra of the antiviral rimantadine using SQMFF and DFT calculations
por: Iramain, Maximiliano A., et al.
Publicado: (2022)

Synthesis and bioevaluation of new tacrine-cinnamic acid hybrids as cholinesterase inhibitors against Alzheimer’s disease
por: Chen, Yao, et al.
Publicado: (2017)

QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer’s Disease Therapy
por: Ramos, Eva, et al.
Publicado: (2019)

Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer’s disease
por: Zhu, Jie, et al.
Publicado: (2018)

Design, synthesis and evaluation of OA-tacrine hybrids as cholinesterase inhibitors with low neurotoxicity and hepatotoxicity against Alzheimer’s disease
por: Yang, Huali, et al.
Publicado: (2023)

Neuroactive Multifunctional Tacrine Congeners with Cholinesterase, Anti-Amyloid Aggregation and Neuroprotective Properties
por: Kozurkova, Maria, et al.
Publicado: (2011)

Neuroprotective derivatives of tacrine that target NMDA receptor and acetyl cholinesterase – Design, synthesis and biological evaluation
por: Remya, Chandran, et al.
Publicado: (2021)

Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities
por: Chrienova, Zofia, et al.
Publicado: (2022)

Cholinesterase inhibitors as Alzheimer's therapeutics
por: Sharma, Kamlesh
Publicado: (2019)

QSAR analysis on tacrine-related acetylcholinesterase inhibitors
por: Wong, Kai Y, et al.
Publicado: (2014)

Novel multitarget-directed tacrine derivatives as potential candidates for the treatment of Alzheimer’s disease
por: Wu, Wen-Yu, et al.
Publicado: (2017)

S(-) and R(+) species derived from antihistaminic promethazine agent: structural and vibrational studies
por: Manzur, María Eugenia, et al.
Publicado: (2019)

Conjugates of Tacrine with Salicylamide as Promising Multitarget Agents for Alzheimer's Disease
por: Grishchenko, Maria V., et al.
Publicado: (2022)

Novel tacrine–benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer’s Disease
por: Fancellu, Gaia, et al.
Publicado: (2019)

Memantine and Cholinesterase Inhibitors: Complementary Mechanisms in the Treatment of Alzheimer’s Disease
por: Parsons, Chris G., et al.
Publicado: (2013)

Odor identification impairment and cholinesterase inhibitor treatment in Alzheimer's disease
por: Motter, Jeffrey N., et al.
Publicado: (2021)

Synergism of antihypertensives and cholinesterase inhibitors in Alzheimer's disease
por: Hu, Ziheng, et al.
Publicado: (2018)

New Multitarget Hybrids Bearing Tacrine and Phenylbenzothiazole Motifs as Potential Drug Candidates for Alzheimer’s Disease
por: Rajeshwari, Rajeshwari, et al.
Publicado: (2019)

Response to cholinesterase inhibitors affects lifespan in Alzheimer’s disease
por: Wattmo, Carina, et al.
Publicado: (2014)

Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer’s disease therapy
por: Dgachi, Youssef, et al.
Publicado: (2018)

New Tacrine Analogs as Acetylcholinesterase Inhibitors — Theoretical Study with Chemometric Analysis
por: Szymański, Paweł, et al.
Publicado: (2013)

Therapeutic Potential of Multifunctional Tacrine Analogues
por: Przybyłowska, Maja, et al.
Publicado: (2019)

A critical review of cholinesterase inhibitors as a treatment modality in Alzheimer's disease
por: S. Schneider, Lon
Publicado: (2000)

Persistent treatment with cholinesterase inhibitors and/or memantine slows clinical progression of Alzheimer disease
por: Rountree, Susan D, et al.
Publicado: (2009)

Development of substituted benzylidene derivatives as novel dual cholinesterase inhibitors for Alzheimer's treatment
por: Gupta, Shraddha Manish, et al.
Publicado: (2023)

Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer’s Disease
por: Makhaeva, Galina F., et al.
Publicado: (2023)

CHRNA7 Polymorphisms and Response to Cholinesterase Inhibitors in Alzheimer's Disease
por: Weng, Pei-Hsuan, et al.
Publicado: (2013)

Synthesis and Biological Evaluation of New Cholinesterase Inhibitors for Alzheimer’s Disease
por: Hussein, Weiam, et al.
Publicado: (2018)

The Investigation of Structure-Activity Relationships of Tacrine Analogues: Electronic-Topological Method
por: Saracoglu, Murat, et al.
Publicado: (2008)

Multitarget Drug Design, Molecular Docking and PLIF Studies of Novel Tacrine−Coumarin Hybrids for the Treatment of Alzheimer’s Disease
por: Fereidoonnezhad, Masood, et al.
Publicado: (2018)

Structure-Based Search for New Inhibitors of Cholinesterases
por: Bajda, Marek, et al.
Publicado: (2013)

Tacrine-Based Hybrids: Past, Present, and Future
por: Bubley, Anna, et al.
Publicado: (2023)

Synthesis of Brominated 2-Phenitidine Derivatives as Valuable Inhibitors of Cholinesterases for the Treatment of Alzheimer’s Disease
por: Abbasi, Muhammad Athar, et al.
Publicado: (2014)

Formulation, Characterization and Evaluation against SH-SY5Y Cells of New Tacrine and Tacrine-MAP Loaded with Lipid Nanoparticles
por: Silva, Sara, et al.
Publicado: (2020)

Novel Tacrine-Scutellarin Hybrids as Multipotent Anti-Alzheimer’s Agents: Design, Synthesis and Biological Evaluation
por: Spilovska, Katarina, et al.
Publicado: (2017)

The Proof-of-Concept of MBA121, a Tacrine–Ferulic Acid Hybrid, for Alzheimer’s Disease Therapy
por: Rodríguez-Ruiz, Emelina R., et al.
Publicado: (2023)

Exploring Mannosylpurines as Copper Chelators and Cholinesterase Inhibitors with Potential for Alzheimer’s Disease
por: Schino, Ignazio, et al.
Publicado: (2022)

New Multifunctional Agents for Potential Alzheimer’s Disease Treatment Based on Tacrine Conjugates with 2-Arylhydrazinylidene-1,3-Diketones
por: Elkina, Natalia A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5ln4qftv2o3ndc1j265crpq5a8