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Plasma lipidomic profiling of thiopurine-induced leukopenia after NUDT15 genotype-guided dosing in Chinese IBD patients

INTRODUCTION: Thiopurines, azathiopurine (AZA) and mercaptopurine (6-MP) have been regularly used in the treatment of inflammatory bowel disease (IBD). Despite optimized dosage adjustment based on the NUDT15 genotypes, some patients still discontinue or change treatment regimens due to thiopurine-in...

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Detalles Bibliográficos
Autores principales:	Li, Pan, Chao, Kang, Hu, Zhanhua, Qin, Lulu, Yang, Ting, Mao, Jing, Zhu, Xia, Hu, Pinjin, Wang, Xueding, Gao, Xiang, Huang, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Nutrition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333543/ https://www.ncbi.nlm.nih.gov/pubmed/37441519 http://dx.doi.org/10.3389/fnut.2023.1138506

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