Locally advanced rectal cancer with dMMR/MSI-H may be excused from surgery after neoadjuvant anti-PD-1 monotherapy: a multiple-center, cohort study

OBJECTIVE: Examine patients with locally advanced rectal cancer (LARC) with deficient mismatch repair (dMMR) or microsatellite instability-high (MSI-H) who received neoadjuvant immunotherapy (nIT), and compare the outcomes of those who chose a watch-and-wait (WW) approach after achieving clinical co...

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Detalles Bibliográficos
Autores principales: Yang, Renfang, Wu, Tao, Yu, Jiehai, Cai, Xinyi, Li, Guoyu, Li, Xiangshu, Huang, Weixin, Zhang, Ya, Wang, Yuqin, Yang, Xudong, Ren, Yongping, Hu, Ruixi, Feng, Qing, Ding, Peirong, Zhang, Xuan, Li, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333582/
https://www.ncbi.nlm.nih.gov/pubmed/37441082
http://dx.doi.org/10.3389/fimmu.2023.1182299

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