Cargando…

Structural transitions in TCTP tumor protein upon binding to the anti-apoptotic protein family member Mcl-1

Translationally Controlled Tumor Protein (TCTP) serves as a pro-survival factor in tumor cells, inhibiting the mitochondrial apoptosis pathway by enhancing the function of anti-apoptotic Bcl-2 family members Mcl-1 and Bcl-xL. TCTP specifically binds to Bcl-xL, preventing Bax-dependent Bcl-xL-induced...

Descripción completa

Detalles Bibliográficos
Autores principales:	Malard, Florian, Sizun, Christina, Thureau, Aurélien, Carlier, Ludovic, Lescop, Ewen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333598/ https://www.ncbi.nlm.nih.gov/pubmed/37201583 http://dx.doi.org/10.1016/j.jbc.2023.104830

Ejemplares similares

The mRNA of TCTP functions as a sponge to maintain homeostasis of TCTP protein levels in hepatocellular carcinoma
por: Liu, Wei, et al.
Publicado: (2020)

Drug Repurposing: Deferasirox Inhibits the Anti-Apoptotic Activity of Mcl-1
por: Bourafai-Aziez, Asma, et al.
Publicado: (2021)

TCTP promotes epithelial–mesenchymal transition in lung adenocarcinoma
por: Sun, Ruilin, et al.
Publicado: (2019)

TCTP in Development and Cancer
por: Koziol, Magdalena J., et al.
Publicado: (2012)

Flexible loop and helix 2 domains of TCTP are the functional domains of dimerized TCTP
por: Lee, Heewon, et al.
Publicado: (2020)

Inhibition of the anti-apoptotic protein MCL-1 severely suppresses human hematopoiesis
por: Bohler, Sheila, et al.
Publicado: (2020)

Marinopyrrole Derivatives with Sulfide Spacers as Selective Disruptors of Mcl-1 Binding to Pro-Apoptotic Protein Bim
por: Cheng, Chunwei, et al.
Publicado: (2014)

Tumor protein Tctp regulates axon development in the embryonic visual system
por: Roque, Cláudio Gouveia, et al.
Publicado: (2016)

Function of translationally controlled tumor protein (TCTP) in Eudrilus eugeniae regeneration
por: Subramanian, Elaiya Raja, et al.
Publicado: (2017)

Sequence Analysis and Comparison of TCTP Proteins from Human Protozoan Parasites
por: Lagunas-Rangel, Francisco Alejandro
Publicado: (2022)

Association of TCTP with Centrosome and Microtubules
por: Jaglarz, Mariusz K., et al.
Publicado: (2012)

Allosteric Inhibition of Anti-Apoptotic MCL-1
por: Lee, Susan, et al.
Publicado: (2016)

The Two Translationally Controlled Tumor Protein Genes, CsTCTP1 and CsTCTP2, Are Negative Modulators in the Cucumis sativus Defense Response to Sphaerotheca fuliginea
por: Meng, Xiangnan, et al.
Publicado: (2018)

The effect of Translationally Controlled Tumour Protein (TCTP) on programmed cell death in plants
por: Hoepflinger, Marion Christine, et al.
Publicado: (2013)

Reduced association of anti-apoptotic protein Mcl-1 with E3 ligase Mule increases the stability of Mcl-1 in breast cancer cells
por: Pervin, S, et al.
Publicado: (2011)

In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-X(L) and Mcl-1 but in the absence of active BH3-only proteins
por: Senft, D, et al.
Publicado: (2015)

Regulation of anti-apoptotic Bcl-2 family protein Mcl-1 by S6 kinase 2
por: Basu, Alakananda, et al.
Publicado: (2017)

Estrogen Regulation of Anti-Apoptotic Bcl-2 Family Member Mcl-1 Expression in Breast Cancer Cells
por: Schacter, Jennifer L., et al.
Publicado: (2014)

Dysregulation of TCTP in Biological Processes and Diseases
por: Bommer, Ulrich-Axel, et al.
Publicado: (2020)

Translationally Controlled Tumour Protein (TCTP) is present in human cornea and increases in herpetic keratitis
por: Batisti, Cinzia, et al.
Publicado: (2012)

14-3-3 proteins regulate Tctp–Rheb interaction for organ growth in Drosophila
por: Le, Thao Phuong, et al.
Publicado: (2016)

Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1
por: Murray, James B., et al.
Publicado: (2019)

ER+ Breast Cancer Strongly Depends on MCL-1 and BCL-xL Anti-Apoptotic Proteins
por: Alcon, Clara, et al.
Publicado: (2021)

Beam Coupling Impedance of the LHC TCTP Collimators
por: Day, Hugo, et al.
Publicado: (2012)

Upregulation of TCTP is associated with cholangiocarcinoma progression and metastasis
por: Phanthaphol, Nattaporn, et al.
Publicado: (2017)

TCTP as a therapeutic target in melanoma treatment
por: Boia-Ferreira, M, et al.
Publicado: (2017)

Insights into the role and regulation of TCTP in skeletal muscle
por: Goodman, Craig A., et al.
Publicado: (2016)

Role of TCTP in Cell Biological and Disease Processes
por: Bommer, Ulrich-Axel, et al.
Publicado: (2021)

Biological Effects of Mammalian Translationally Controlled Tumor Protein (TCTP) on Cell Death, Proliferation, and Tumorigenesis
por: Nagano-Ito, Michiyo, et al.
Publicado: (2012)

Expression of Translationally Controlled Tumor Protein (TCTP) Gene of Dirofilaria immitis Guided by Transcriptomic Screening
por: Fu, Yan, et al.
Publicado: (2014)

Some Biological Consequences of the Inhibition of Na,K-ATPase by Translationally Controlled Tumor Protein (TCTP)
por: Jung, Jiwon, et al.
Publicado: (2018)

AtTCTP2 mRNA and protein movement correlates with formation of adventitious roots in tobacco
por: Toscano-Morales, Roberto, et al.
Publicado: (2015)

Role of Translationally Controlled Tumor Protein (TCTP) in the Development of Hypertension and Related Diseases in Mouse Models
por: Maeng, Jeehye, et al.
Publicado: (2022)

Novel post-transcriptional and post-translational regulation of pro-apoptotic protein BOK and anti-apoptotic protein Mcl-1 determine the fate of breast cancer cells to survive or die
por: Onyeagucha, Benjamin, et al.
Publicado: (2017)

Dual inhibition of anti-apoptotic proteins BCL-XL and MCL-1 enhances cytotoxicity of Nasopharyngeal carcinoma cells
por: Abdul Rahman, Siti Fairus, et al.
Publicado: (2022)

Myeloid expression of the anti-apoptotic protein Mcl1 is required in anti-myeloperoxidase vasculitis but myeloperoxidase inhibition is not protective
por: Florez-Barros, Fernanda, et al.
Publicado: (2023)

Long distance movement of an Arabidopsis Translationally Controlled Tumor Protein (AtTCTP2) mRNA and protein in tobacco
por: Toscano-Morales, Roberto, et al.
Publicado: (2014)

Characterization of a Novel Binding Protein for Fortilin/TCTP — Component of a Defense Mechanism against Viral Infection in Penaeus monodon
por: Panrat, Tanate, et al.
Publicado: (2012)

Interaction of antihistaminic drugs with human translationally controlled tumor protein (TCTP) as novel approach for differentiation therapy
por: Seo, Ean-Jeong, et al.
Publicado: (2016)

Long-Distance Movement of Solanum tuberosum Translationally Controlled Tumor Protein (StTCTP) mRNA
por: Xoconostle-Morán, Brenda Beatriz, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2r6mjua7jqtpnms3okpd0a55cv