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Development of KEAP1-targeting PROTAC and its antioxidant properties: In vitro and in vivo

Oxidative stress due to abnormal accumulation of reactive oxygen species (ROS) is an initiator of a large number of human diseases, and thus, the elimination and prevention of excessive ROS are important aspects of preventing the development of such diseases. Nuclear factor erythroid 2-related facto...

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Detalles Bibliográficos
Autores principales: Park, Se Yong, Gurung, Raju, Hwang, Jung Ho, Kang, Ju-Hee, Jung, Hyun Jin, Zeb, Alam, Hwang, Jong-Ik, Park, Sung Jean, Maeng, Han-Joo, Shin, Dongyun, Oh, Seung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333676/
https://www.ncbi.nlm.nih.gov/pubmed/37348157
http://dx.doi.org/10.1016/j.redox.2023.102783