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Development of KEAP1-targeting PROTAC and its antioxidant properties: In vitro and in vivo
Oxidative stress due to abnormal accumulation of reactive oxygen species (ROS) is an initiator of a large number of human diseases, and thus, the elimination and prevention of excessive ROS are important aspects of preventing the development of such diseases. Nuclear factor erythroid 2-related facto...
Autores principales: | Park, Se Yong, Gurung, Raju, Hwang, Jung Ho, Kang, Ju-Hee, Jung, Hyun Jin, Zeb, Alam, Hwang, Jong-Ik, Park, Sung Jean, Maeng, Han-Joo, Shin, Dongyun, Oh, Seung Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333676/ https://www.ncbi.nlm.nih.gov/pubmed/37348157 http://dx.doi.org/10.1016/j.redox.2023.102783 |
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