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A review of frailty instruments in human medicine and proposal of a frailty instrument for dogs

Over the last few decades, frailty has become a pillar of research and clinical assessment in human gerontology. This complex syndrome, characterized by loss of physiologic reserves leading to decreased resilience to stressors, is of critical importance because it predicts higher risks of poor healt...

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Autores principales: Melvin, Rachel L., Ruple, Audrey, Pearson, Elizabeth B., Olby, Natasha J., Fitzpatrick, Annette L., Creevy, Kate E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333704/
https://www.ncbi.nlm.nih.gov/pubmed/37441560
http://dx.doi.org/10.3389/fvets.2023.1139308
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author Melvin, Rachel L.
Ruple, Audrey
Pearson, Elizabeth B.
Olby, Natasha J.
Fitzpatrick, Annette L.
Creevy, Kate E.
author_facet Melvin, Rachel L.
Ruple, Audrey
Pearson, Elizabeth B.
Olby, Natasha J.
Fitzpatrick, Annette L.
Creevy, Kate E.
author_sort Melvin, Rachel L.
collection PubMed
description Over the last few decades, frailty has become a pillar of research and clinical assessment in human gerontology. This complex syndrome, characterized by loss of physiologic reserves leading to decreased resilience to stressors, is of critical importance because it predicts higher risks of poor health outcomes, including mortality. Thus, identifying frailty among the elderly human population has become a key focus of gerontology. This narrative review presents current scientific literature on frailty in both humans and animals. The authors discuss the need for an accessible frailty instrument for companion dogs suitable for general use in veterinary medicine and the advances that would be facilitated by this instrument. A phenotypic frailty instrument for companion dogs, utilizing components that are easily collected by owners, or in the general practice setting, is proposed. The authors elaborate on the domains (physical condition, physical activity, mobility, strength, cognitive task performance, and social behavior), factors that will be included, and the data from the Dog Aging Project that inform each domain.
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spelling pubmed-103337042023-07-12 A review of frailty instruments in human medicine and proposal of a frailty instrument for dogs Melvin, Rachel L. Ruple, Audrey Pearson, Elizabeth B. Olby, Natasha J. Fitzpatrick, Annette L. Creevy, Kate E. Front Vet Sci Veterinary Science Over the last few decades, frailty has become a pillar of research and clinical assessment in human gerontology. This complex syndrome, characterized by loss of physiologic reserves leading to decreased resilience to stressors, is of critical importance because it predicts higher risks of poor health outcomes, including mortality. Thus, identifying frailty among the elderly human population has become a key focus of gerontology. This narrative review presents current scientific literature on frailty in both humans and animals. The authors discuss the need for an accessible frailty instrument for companion dogs suitable for general use in veterinary medicine and the advances that would be facilitated by this instrument. A phenotypic frailty instrument for companion dogs, utilizing components that are easily collected by owners, or in the general practice setting, is proposed. The authors elaborate on the domains (physical condition, physical activity, mobility, strength, cognitive task performance, and social behavior), factors that will be included, and the data from the Dog Aging Project that inform each domain. Frontiers Media S.A. 2023-06-27 /pmc/articles/PMC10333704/ /pubmed/37441560 http://dx.doi.org/10.3389/fvets.2023.1139308 Text en Copyright © 2023 Melvin, Ruple, Pearson, Olby, Fitzpatrick and Creevy. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Melvin, Rachel L.
Ruple, Audrey
Pearson, Elizabeth B.
Olby, Natasha J.
Fitzpatrick, Annette L.
Creevy, Kate E.
A review of frailty instruments in human medicine and proposal of a frailty instrument for dogs
title A review of frailty instruments in human medicine and proposal of a frailty instrument for dogs
title_full A review of frailty instruments in human medicine and proposal of a frailty instrument for dogs
title_fullStr A review of frailty instruments in human medicine and proposal of a frailty instrument for dogs
title_full_unstemmed A review of frailty instruments in human medicine and proposal of a frailty instrument for dogs
title_short A review of frailty instruments in human medicine and proposal of a frailty instrument for dogs
title_sort review of frailty instruments in human medicine and proposal of a frailty instrument for dogs
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333704/
https://www.ncbi.nlm.nih.gov/pubmed/37441560
http://dx.doi.org/10.3389/fvets.2023.1139308
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