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Versatile delivery platform for nucleic acids, negatively charged protein drugs, and genome-editing ribonucleoproteins using a multi-step transformable polyrotaxane
Various biopharmaceuticals, such as nucleic acids, proteins, and genome-editing molecules, have been developed. Generally, carriers are prepared for each biopharmaceutical to deliver it intracellularly; thus, the applications of individual carriers are limited. Moreover, the development of carriers...
Autores principales: | Taharabaru, Toru, Kihara, Takuya, Onodera, Risako, Kogo, Tetsuya, Wen, Yuting, Li, Jun, Motoyama, Keiichi, Higashi, Taishi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333717/ https://www.ncbi.nlm.nih.gov/pubmed/37441133 http://dx.doi.org/10.1016/j.mtbio.2023.100690 |
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