A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability

While cellular metabolism impacts the DNA damage response, a systematic understanding of the metabolic requirements that are crucial for DNA damage repair has yet to be achieved. Here, we investigate the metabolic enzymes and processes that are essential for the resolution of DNA damage. By integrat...

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Detalles Bibliográficos
Autores principales: Moretton, Amandine, Kourtis, Savvas, Gañez Zapater, Antoni, Calabrò, Chiara, Espinar Calvo, Maria Lorena, Fontaine, Frédéric, Darai, Evangelia, Abad Cortel, Etna, Block, Samuel, Pascual‐Reguant, Laura, Pardo‐Lorente, Natalia, Ghose, Ritobrata, Vander Heiden, Matthew G, Janic, Ana, Müller, André C, Loizou, Joanna I, Sdelci, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333845/
https://www.ncbi.nlm.nih.gov/pubmed/37259925
http://dx.doi.org/10.15252/msb.202211267

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