Asbestos accelerates disease onset in a genetic model of malignant pleural mesothelioma

Hypothesis: Asbestos-driven inflammation contributes to malignant pleural mesothelioma beyond the acquisition of rate-limiting mutations. Methods: Genetically modified conditional allelic mice that were previously shown to develop mesothelioma in the absence of exposure to asbestos were induced with...

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Detalles Bibliográficos
Autores principales: Farahmand, Pooyeh, Gyuraszova, Katarina, Rooney, Claire, Raffo-Iraolagoitia, Ximena L., Jayasekera, Geeshath, Hedley, Ann, Johnson, Emma, Chernova, Tatyana, Malviya, Gaurav, Hall, Holly, Monteverde, Tiziana, Blyth, Kevin, Duffin, Rodger, Carlin, Leo M., Lewis, David, Le Quesne, John, MacFarlane, Marion, Murphy, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333928/
https://www.ncbi.nlm.nih.gov/pubmed/37441092
http://dx.doi.org/10.3389/ftox.2023.1200650

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