Cargando…

Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial

OBJECTIVE: The diagnosis and treatment of breast cancer is associated with significant distress that has huge impact on survivors’ quality of life. The objective of this study is to assess the effectiveness of an integrated intervention “Moving on After Breast Cancer (ABC) Plus culturally adapted Co...

Descripción completa

Detalles Bibliográficos
Autores principales: Husain, Nusrat, Kiran, Tayyeba, Chaudhry, Imran B, Sultan, Sarwat, Dawood, Saima, Lunat, Farah, Nizami, Asad, Shanahan, Lisa, Qureshi, Afshan, Un Nisa, Zaib, Husain, Mina, Shakoor, Suleman, Alvi, Mohsin H, Zadeh, Zainab, Memon, Rakhshi, Chaudhry, Nasim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333993/
https://www.ncbi.nlm.nih.gov/pubmed/37441193
http://dx.doi.org/10.1177/20503121231177549
_version_ 1785070778301022208
author Husain, Nusrat
Kiran, Tayyeba
Chaudhry, Imran B
Sultan, Sarwat
Dawood, Saima
Lunat, Farah
Nizami, Asad
Shanahan, Lisa
Qureshi, Afshan
Un Nisa, Zaib
Husain, Mina
Shakoor, Suleman
Alvi, Mohsin H
Zadeh, Zainab
Memon, Rakhshi
Chaudhry, Nasim
author_facet Husain, Nusrat
Kiran, Tayyeba
Chaudhry, Imran B
Sultan, Sarwat
Dawood, Saima
Lunat, Farah
Nizami, Asad
Shanahan, Lisa
Qureshi, Afshan
Un Nisa, Zaib
Husain, Mina
Shakoor, Suleman
Alvi, Mohsin H
Zadeh, Zainab
Memon, Rakhshi
Chaudhry, Nasim
author_sort Husain, Nusrat
collection PubMed
description OBJECTIVE: The diagnosis and treatment of breast cancer is associated with significant distress that has huge impact on survivors’ quality of life. The objective of this study is to assess the effectiveness of an integrated intervention “Moving on After Breast Cancer (ABC) Plus culturally adapted Cognitive Behavior Therapy” (Moving on ABC Plus). METHOD: This is a randomized controlled trial that aims to recruit 354 breast cancer survivors from the inpatient and outpatient oncology departments in public and private hospitals in Karachi, Hyderabad, Lahore, Multan, and Rawalpindi in Pakistan. Patients scoring 10 or above on either the Patient Health Questionnaire—9 and/or the Generalized Anxiety Disorder scale (GAD-7) will be recruited. Baseline assessments will include Functional Assessment of Cancer Therapy—Breast; EuroQol-5D; Multidimensional Scale for Perceived Social Support; Intrusive Thoughts Scale; and Rosenberg Self-Esteem Scale. Participants randomized into intervention arm, Moving on ABC Plus, will receive 12 individual therapy sessions over 4 months. Follow-up will be completed at 4- and 6-month post-randomization, using all baseline instruments along with the Client Satisfaction Questionnaire (CSQ-8). We will also explore the participants’, their family members’, and the therapists’ experiences of the trial and intervention. RESULTS: We will be assessing the effectiveness of intervention in reducing depression and anxiety in breast cancer survivors as a primary outcome of the trial. The secondary outcomes will include effectiveness of intervention in terms of reduction in intrusive thoughts and improvement in health-related quality of life, self-esteem, and perceived social support. CONCLUSION: The results of the study will inform the design of a future larger randomized control trial with long-term follow-up.
format Online
Article
Text
id pubmed-10333993
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-103339932023-07-12 Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial Husain, Nusrat Kiran, Tayyeba Chaudhry, Imran B Sultan, Sarwat Dawood, Saima Lunat, Farah Nizami, Asad Shanahan, Lisa Qureshi, Afshan Un Nisa, Zaib Husain, Mina Shakoor, Suleman Alvi, Mohsin H Zadeh, Zainab Memon, Rakhshi Chaudhry, Nasim SAGE Open Med Study Protocol OBJECTIVE: The diagnosis and treatment of breast cancer is associated with significant distress that has huge impact on survivors’ quality of life. The objective of this study is to assess the effectiveness of an integrated intervention “Moving on After Breast Cancer (ABC) Plus culturally adapted Cognitive Behavior Therapy” (Moving on ABC Plus). METHOD: This is a randomized controlled trial that aims to recruit 354 breast cancer survivors from the inpatient and outpatient oncology departments in public and private hospitals in Karachi, Hyderabad, Lahore, Multan, and Rawalpindi in Pakistan. Patients scoring 10 or above on either the Patient Health Questionnaire—9 and/or the Generalized Anxiety Disorder scale (GAD-7) will be recruited. Baseline assessments will include Functional Assessment of Cancer Therapy—Breast; EuroQol-5D; Multidimensional Scale for Perceived Social Support; Intrusive Thoughts Scale; and Rosenberg Self-Esteem Scale. Participants randomized into intervention arm, Moving on ABC Plus, will receive 12 individual therapy sessions over 4 months. Follow-up will be completed at 4- and 6-month post-randomization, using all baseline instruments along with the Client Satisfaction Questionnaire (CSQ-8). We will also explore the participants’, their family members’, and the therapists’ experiences of the trial and intervention. RESULTS: We will be assessing the effectiveness of intervention in reducing depression and anxiety in breast cancer survivors as a primary outcome of the trial. The secondary outcomes will include effectiveness of intervention in terms of reduction in intrusive thoughts and improvement in health-related quality of life, self-esteem, and perceived social support. CONCLUSION: The results of the study will inform the design of a future larger randomized control trial with long-term follow-up. SAGE Publications 2023-06-29 /pmc/articles/PMC10333993/ /pubmed/37441193 http://dx.doi.org/10.1177/20503121231177549 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Study Protocol
Husain, Nusrat
Kiran, Tayyeba
Chaudhry, Imran B
Sultan, Sarwat
Dawood, Saima
Lunat, Farah
Nizami, Asad
Shanahan, Lisa
Qureshi, Afshan
Un Nisa, Zaib
Husain, Mina
Shakoor, Suleman
Alvi, Mohsin H
Zadeh, Zainab
Memon, Rakhshi
Chaudhry, Nasim
Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial
title Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial
title_full Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial
title_fullStr Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial
title_full_unstemmed Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial
title_short Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial
title_sort integrated moving on after breast cancer and culturally adapted cognitive behavior therapy intervention for depression and anxiety among pakistani women with breast cancer: protocol of a randomized controlled trial
topic Study Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333993/
https://www.ncbi.nlm.nih.gov/pubmed/37441193
http://dx.doi.org/10.1177/20503121231177549
work_keys_str_mv AT husainnusrat integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT kirantayyeba integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT chaudhryimranb integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT sultansarwat integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT dawoodsaima integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT lunatfarah integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT nizamiasad integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT shanahanlisa integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT qureshiafshan integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT unnisazaib integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT husainmina integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT shakoorsuleman integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT alvimohsinh integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT zadehzainab integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT memonrakhshi integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial
AT chaudhrynasim integratedmovingonafterbreastcancerandculturallyadaptedcognitivebehaviortherapyinterventionfordepressionandanxietyamongpakistaniwomenwithbreastcancerprotocolofarandomizedcontrolledtrial