Hybrid neural network approaches to predict drug–target binding affinity for drug repurposing: screening for potential leads for Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative disease that primarily affects elderly individuals. Recent studies have found that sigma-1 receptor (S1R) agonists can maintain endoplasmic reticulum stress homeostasis, reduce neuronal apoptosis, and enhance mitochondrial function and autophagy, makin...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Xialin, Li, Zhuojian, Chen, Guanxing, Yin, Yiyang, Chen, Calvin Yu-Chian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334190/
https://www.ncbi.nlm.nih.gov/pubmed/37441162
http://dx.doi.org/10.3389/fmolb.2023.1227371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334190/
https://www.ncbi.nlm.nih.gov/pubmed/37441162
http://dx.doi.org/10.3389/fmolb.2023.1227371

Ejemplares similares