Cargando…

Paclitaxel-loaded ginsenoside Rg3 liposomes for drug-resistant cancer therapy by dual targeting of the tumor microenvironment and cancer cells

INTRODUCTION: Inherent or acquired resistance to paclitaxel (PTX) is a pivotal challenge for chemotherapy treatment of multidrug-resistant (MDR) breast cancer. Although various targeted drug-delivery systems, including nanoparticles and liposomes, are effective for MDR cancer treatment, their effica...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Ying, Wang, Anni, Zhang, Shuya, Kim, Jisu, Xia, Jiaxuan, Zhang, Fengxue, Wang, Dan, Wang, Qi, Wang, Jianxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334248/ https://www.ncbi.nlm.nih.gov/pubmed/36167294 http://dx.doi.org/10.1016/j.jare.2022.09.007

Ejemplares similares

Targeting therapy and tumor microenvironment remodeling of triple-negative breast cancer by ginsenoside Rg3 based liposomes
por: Xia, Jiaxuan, et al.
Publicado: (2022)

Effect of the structure of ginsenosides on the in vivo fate of their liposomes
por: Chen, Chen, et al.
Publicado: (2022)

Versatile ginsenoside Rg3 liposomes inhibit tumor metastasis by capturing circulating tumor cells and destroying metastatic niches
por: Xia, Jiaxuan, et al.
Publicado: (2022)

Novel ginsenoside-based multifunctional liposomal delivery system for combination therapy of gastric cancer
por: Hong, Chao, et al.
Publicado: (2019)

Polymer-Based Wound Dressings Loaded with Ginsenoside Rg3
por: Yang, Jiali, et al.
Publicado: (2023)

One Stone Four Birds: A Novel Liposomal Delivery System Multi-functionalized with Ginsenoside Rh2 for Tumor Targeting Therapy
por: Hong, Chao, et al.
Publicado: (2020)

Ginsenoside Rg5 Sensitizes Paclitaxel—Resistant Human Cervical-Adeno-Carcinoma Cells to Paclitaxel—And Enhances the Anticancer Effect of Paclitaxel
por: Ramesh, Janani, et al.
Publicado: (2022)

Remote loading paclitaxel–doxorubicin prodrug into liposomes for cancer combination therapy
por: Yu, Jiang, et al.
Publicado: (2020)

Efficacy of dual-functional liposomes containing paclitaxel for treatment of lung cancer
por: Wang, Rong-Hua, et al.
Publicado: (2017)

Ginsenoside-Rg5 induces apoptosis and DNA damage in human cervical cancer cells
por: LIANG, LI-DAN, et al.
Publicado: (2015)

The positive effects of Ginsenoside Rg1 upon the hematopoietic microenvironment in a D-Galactose-induced aged rat model
por: Hu, Wenxu, et al.
Publicado: (2015)

Effects of ginsenoside Rg3 on epigenetic modification in ovarian cancer cells
por: Zhao, Lingqin, et al.
Publicado: (2019)

Anti-glioma effect of ginseng-derived exosomes-like nanoparticles by active blood–brain-barrier penetration and tumor microenvironment modulation
por: Kim, Jisu, et al.
Publicado: (2023)

Evaluation of 20(S)-ginsenoside Rg3 loaded hydrogel for the treatment of perianal ulcer in a rat model
por: Jin, Longhai, et al.
Publicado: (2022)

Protective effect and mechanism of ginsenoside Rg2 on atherosclerosis
por: Xue, Qianqian, et al.
Publicado: (2023)

Phosphoproteomic analysis of the antitumor effects of ginsenoside Rg3 in human breast cancer cells
por: Zou, Mingjin, et al.
Publicado: (2018)

In Vitro/In Vivo Metabolism of Ginsenoside Rg5 in Rat Using Ultra-Performance Liquid Chromatography/Quadrupole-Time-of-Flight Mass Spectrometry
por: Hong, Chao, et al.
Publicado: (2018)

A systematic review and meta-analysis of Ginsenoside-Rg1 (G-Rg1) in experimental ischemic stroke
por: Xie, Cheng-long, et al.
Publicado: (2015)

Protective effect of ginsenoside Rg1 on lidocaine-induced apoptosis
por: LI, HUI, et al.
Publicado: (2014)

Ginsenoside Rg3 inhibits the biological activity of SGC‐7901
por: Yang, Qing, et al.
Publicado: (2020)

Ginsenoside Rg3 Alleviates Antithyroid Cancer Drug Vandetanib-Induced QT Interval Prolongation
por: Zhang, Juan, et al.
Publicado: (2021)

Synthesis of Paclitaxel Derivatives for Remote Loading into Liposomes and Improved Therapeutic Effect
por: Xu, Xiangwei, et al.
Publicado: (2022)

Anti-Angiogenic Properties of Ginsenoside Rg3
por: Nakhjavani, Maryam, et al.
Publicado: (2020)

Pharmacological activities of ginsenoside Rg5 (Review)
por: Liu, Ming-Yang, et al.
Publicado: (2021)

Dual Targeting Biomimetic Liposomes for Paclitaxel/DNA Combination Cancer Treatment
por: Liu, Guo-Xia, et al.
Publicado: (2014)

Comparative Pharmacokinetics of Ginsenoside Rg(3) and Ginsenoside Rh(2) after Oral Administration of Ginsenoside Rg(3) in Normal and Walker 256 Tumor-bearing Rats
por: Fan, He, et al.
Publicado: (2016)

Graphene Oxide Nanoparticle–Loaded Ginsenoside Rg3 Improves Photodynamic Therapy in Inhibiting Malignant Progression and Stemness of Osteosarcoma
por: Lu, Shou-Liang, et al.
Publicado: (2021)

Anti-adipogenic Effects and Mechanisms of Ginsenoside Rg3 in Pre-adipocytes and Obese Mice
por: Zhang, Longyun, et al.
Publicado: (2017)

Simple weak-acid derivatives of paclitaxel for remote loading into liposomes and improved therapeutic effects
por: Yu, Jiang, et al.
Publicado: (2020)

Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer in mice
por: Liu, Tai-Guo, et al.
Publicado: (2009)

Novel Antidepressant Mechanism of Ginsenoside Rg1 in Regulating the Dysfunction of the Glutamatergic System in Astrocytes
por: Zhang, Ningning, et al.
Publicado: (2022)

Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions
por: Mohanan, Padmanaban, et al.
Publicado: (2018)

Ginsenoside Rg2 Attenuated Trastuzumab-Induced Cardiotoxicity in Rats
por: Liu, Guang, et al.
Publicado: (2022)

Evaluation of the gastroprotective effects of 20 (S)-ginsenoside Rg3 on gastric ulcer models in mice
por: Zhang, Kai, et al.
Publicado: (2019)

The synthesis of a nanodrug using metal-based nanozymes conjugated with ginsenoside Rg3 for pancreatic cancer therapy
por: Zhao, Xiaoxiong, et al.
Publicado: (2021)

20(S)-ginsenoside Rg3 promotes senescence and apoptosis in gallbladder cancer cells via the p53 pathway
por: Zhang, Fei, et al.
Publicado: (2015)

Ginsenoside Rg3 targets cancer stem cells and tumor angiogenesis to inhibit colorectal cancer progression in vivo
por: Tang, Yu-Chen, et al.
Publicado: (2017)

Dual-modified cationic liposomes loaded with paclitaxel and survivin siRNA for targeted imaging and therapy of cancer stem cells in brain glioma
por: Sun, Xiyang, et al.
Publicado: (2018)

Relationship Between Ginsenoside Rg3 and Metabolic Syndrome
por: Lee, Hyunji, et al.
Publicado: (2020)

Ginsenoside Rg1 attenuates liver injury induced by D-galactose in mice
por: Xiao, Ming-He, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_f48uamq3ocf967b84uujm4v1vl