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YTHDC1 positively regulates PTEN expression and plays a critical role in cisplatin resistance of bladder cancer

Activation of PI3K/AKT signalling by PTEN loss significantly enhances chemoresistance in bladder cancer. This study aims to evaluate PTEN regulation and identify targets that could be used to relieve chemoresistance. Expression of YTHDC1, γ‐H2AX and PTEN were detected by IHC assay. Cell Counting Kit...

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Detalles Bibliográficos
Autores principales: Su, Yinjie, Wang, Bo, Huang, Jian, Huang, Ming, Lin, Tianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334275/
https://www.ncbi.nlm.nih.gov/pubmed/37070134
http://dx.doi.org/10.1111/cpr.13404