Cargando…
YTHDC1 positively regulates PTEN expression and plays a critical role in cisplatin resistance of bladder cancer
Activation of PI3K/AKT signalling by PTEN loss significantly enhances chemoresistance in bladder cancer. This study aims to evaluate PTEN regulation and identify targets that could be used to relieve chemoresistance. Expression of YTHDC1, γ‐H2AX and PTEN were detected by IHC assay. Cell Counting Kit...
Autores principales: | Su, Yinjie, Wang, Bo, Huang, Jian, Huang, Ming, Lin, Tianxin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334275/ https://www.ncbi.nlm.nih.gov/pubmed/37070134 http://dx.doi.org/10.1111/cpr.13404 |
Ejemplares similares
-
Hypoxia-elevated circELP3 contributes to bladder cancer progression and cisplatin resistance
por: Su, Yinjie, et al.
Publicado: (2019) -
YTHDC1 mitigates ischemic stroke by promoting Akt phosphorylation through destabilizing PTEN mRNA
por: Zhang, Zhaolong, et al.
Publicado: (2020) -
circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway
por: Su, Yinjie, et al.
Publicado: (2020) -
Correction to: circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway
por: Su, Yinjie, et al.
Publicado: (2021) -
The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression
por: Yan, Bin, et al.
Publicado: (2023)