Radix Paeoniae Alba attenuates Radix Bupleuri-induced hepatotoxicity by modulating gut microbiota to alleviate the inhibition of saikosaponins on glutathione synthetase

Radix Bupleuri (RB) is commonly used to treat depression, but it can also lead to hepatotoxicity after long-term use. In many anti-depression prescriptions, RB is often used in combination with Radix Paeoniae Alba (RPA) as an herb pair. However, whether RPA can alleviate RB-induced hepatotoxicity re...

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Detalles Bibliográficos
Autores principales: Chen, Congcong, Gong, Wenxia, Tian, Junshen, Gao, Xiaoxia, Qin, Xuemei, Du, Guanhua, Zhou, Yuzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334278/
https://www.ncbi.nlm.nih.gov/pubmed/37440914
http://dx.doi.org/10.1016/j.jpha.2023.04.016

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