Adaptation of the intact proviral DNA assay to a nanowell-based digital PCR platform

Quantification of intact proviruses is a critical measurement in HIV cure studies both in vitro and in vivo. The widely adopted ‘intact proviral DNA assay’ (IPDA), designed to discriminate and quantify genetically intact HIV proviruses based on detection of two HIV sequence-specific targets, was ori...

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Detalles Bibliográficos
Autores principales: Tumpach, Carolin, Cochrane, Catherine R., Kim, Youry, Ong, Jesslyn, Rhodes, Ajantha, Angelovich, Thomas A., Churchill, Melissa J., Lewin, Sharon R., Telwatte, Sushama, Roche, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334350/
https://www.ncbi.nlm.nih.gov/pubmed/37440871
http://dx.doi.org/10.1016/j.jve.2023.100335

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