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The Effects of Peroxisome Proliferator-Activated Receptor-Delta Modulator ASP1128 in Patients at Risk for Acute Kidney Injury Following Cardiac Surgery

INTRODUCTION: Peroxisome proliferator-activated receptor δ (PPARδ) plays a central role in modulating mitochondrial function in ischemia-reperfusion injury. The novel PPARδ modulator, ASP1128, was evaluated. METHODS: A randomized, double-blind, placebo-controlled, biomarker assignment-driven, multic...

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Detalles Bibliográficos
Autores principales:	van Till, J.W. Olivier, Nojima, Hiroyuki, Kameoka, Chisato, Hayashi, Chieri, Sakatani, Taishi, Washburn, T. Benton, Molitoris, Bruce A., Shaw, Andrew D., Engelman, Daniel T., Kellum, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334402/ https://www.ncbi.nlm.nih.gov/pubmed/37441472 http://dx.doi.org/10.1016/j.ekir.2023.04.004

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