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Ancient transcriptional regulators can easily evolve new pair-wise cooperativity

Cells regulate gene expression by the specific binding of transcription regulators to cis-regulatory sequences. Pair-wise cooperativity between regulators—whereby two different regulators physically interact and bind DNA in a cooperative manner—is common and permits complex modes of gene regulation....

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Detalles Bibliográficos
Autores principales: Fowler, Kyle R., Leon, Fredrick, Johnson, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334809/
https://www.ncbi.nlm.nih.gov/pubmed/37399378
http://dx.doi.org/10.1073/pnas.2302445120