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Ancient transcriptional regulators can easily evolve new pair-wise cooperativity
Cells regulate gene expression by the specific binding of transcription regulators to cis-regulatory sequences. Pair-wise cooperativity between regulators—whereby two different regulators physically interact and bind DNA in a cooperative manner—is common and permits complex modes of gene regulation....
Autores principales: | Fowler, Kyle R., Leon, Fredrick, Johnson, Alexander D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334809/ https://www.ncbi.nlm.nih.gov/pubmed/37399378 http://dx.doi.org/10.1073/pnas.2302445120 |
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