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Glutamine ameliorates Bungarus multicinctus venom-induced lung and heart injury through HSP70: NF-κB p65 and P53/PUMA signaling pathways involved

BACKGROUND: Bungarus multicinctus is one of the most dangerous venomous snakes prone to cardiopulmonary damage with extremely high mortality. In our previous work, we found that glutamine (Gln) and glutamine synthetase (GS) in pig serum were significantly reduced after Bungarus multicinctus bite. In...

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Detalles Bibliográficos
Autores principales: Li, Yalan, Guan, Zhezhe, Hu, Shaocong, Huang, Zhi, He, Dongling, Cheng, Xiaoyang, Song, Tianlin, Mo, Caifeng, Xiao, Manqi, Huang, Yue, Wei, Yuanmei, Zhou, Yi, Zhang, Xuerong, Liao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP) 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334810/
https://www.ncbi.nlm.nih.gov/pubmed/37441002
http://dx.doi.org/10.1590/1678-9199-JVATITD-2022-0080