The efficacy of the benzimidazoles oxfendazole and flubendazole against Litomosoides sigmodontis is dependent on the adaptive and innate immune system

Filarial nematodes can cause debilitating diseases such as lymphatic filariasis and onchocerciasis. Oxfendazole (OXF) is one promising macrofilaricidal candidate with improved oral availability compared to flubendazole (FBZ), and OXF is currently under preparation for phase 2 clinical trials in fila...

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Detalles Bibliográficos
Autores principales: Risch, Frederic, Scheunemann, Johanna F., Reichwald, Julia J., Lenz, Benjamin, Ehrens, Alexandra, Gal, Joséphine, Fercoq, Frédéric, Koschel, Marianne, Fendler, Martina, Hoerauf, Achim, Martin, Coralie, Hübner, Marc P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335397/
https://www.ncbi.nlm.nih.gov/pubmed/37440891
http://dx.doi.org/10.3389/fmicb.2023.1213143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335397/
https://www.ncbi.nlm.nih.gov/pubmed/37440891
http://dx.doi.org/10.3389/fmicb.2023.1213143

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