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Challenges of SARS-CoV-2 genomic surveillance in India during low positivity rate scenario

Being the second most populous country in the world, India presents valuable lessons for the world about dealing with the SARS-CoV-2 pandemic. From this perspective, we attempted a retrospective evaluation of India’s SARS-CoV-2 genomic surveillance strategy and also gave some recommendations for und...

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Autores principales: Tomar, Siddharth Singh, Khairnar, Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335399/
https://www.ncbi.nlm.nih.gov/pubmed/37441634
http://dx.doi.org/10.3389/fpubh.2023.1117602
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author Tomar, Siddharth Singh
Khairnar, Krishna
author_facet Tomar, Siddharth Singh
Khairnar, Krishna
author_sort Tomar, Siddharth Singh
collection PubMed
description Being the second most populous country in the world, India presents valuable lessons for the world about dealing with the SARS-CoV-2 pandemic. From this perspective, we attempted a retrospective evaluation of India’s SARS-CoV-2 genomic surveillance strategy and also gave some recommendations for undertaking effective genomic surveillance. The dynamics of the COVID-19 pandemic are continuously evolving, and there is a dire need to modulate the genomic surveillance strategy accordingly. The pandemic is now settling towards a low positivity rate scenario, so it is required to revise the practices and policies formulated for a high positivity rate scenario. The perspective also recommends adopting a decentralised approach for SARS-CoV-2 genomic surveillance with a focus on optimising the workflow of SARS-CoV-2 genomic surveillance to ensure early detection of emerging variants, especially in the low positivity rate scenario. The perspective emphasises a key observation that the SARS-CoV-2 genomic surveillance is an important mitigation effort during the pandemic, the guards of such mitigation efforts should not be lowered during the low positivity rate scenario. We attempt to highlight the limitations faced by the Indian healthcare administration during the SARS-CoV-2 genomic surveillance and, simultaneously, suggest policy interventions derived from our first-hand experience, which may be implementable in a vast, populated country like India.
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spelling pubmed-103353992023-07-12 Challenges of SARS-CoV-2 genomic surveillance in India during low positivity rate scenario Tomar, Siddharth Singh Khairnar, Krishna Front Public Health Public Health Being the second most populous country in the world, India presents valuable lessons for the world about dealing with the SARS-CoV-2 pandemic. From this perspective, we attempted a retrospective evaluation of India’s SARS-CoV-2 genomic surveillance strategy and also gave some recommendations for undertaking effective genomic surveillance. The dynamics of the COVID-19 pandemic are continuously evolving, and there is a dire need to modulate the genomic surveillance strategy accordingly. The pandemic is now settling towards a low positivity rate scenario, so it is required to revise the practices and policies formulated for a high positivity rate scenario. The perspective also recommends adopting a decentralised approach for SARS-CoV-2 genomic surveillance with a focus on optimising the workflow of SARS-CoV-2 genomic surveillance to ensure early detection of emerging variants, especially in the low positivity rate scenario. The perspective emphasises a key observation that the SARS-CoV-2 genomic surveillance is an important mitigation effort during the pandemic, the guards of such mitigation efforts should not be lowered during the low positivity rate scenario. We attempt to highlight the limitations faced by the Indian healthcare administration during the SARS-CoV-2 genomic surveillance and, simultaneously, suggest policy interventions derived from our first-hand experience, which may be implementable in a vast, populated country like India. Frontiers Media S.A. 2023-06-27 /pmc/articles/PMC10335399/ /pubmed/37441634 http://dx.doi.org/10.3389/fpubh.2023.1117602 Text en Copyright © 2023 Tomar and Khairnar. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Tomar, Siddharth Singh
Khairnar, Krishna
Challenges of SARS-CoV-2 genomic surveillance in India during low positivity rate scenario
title Challenges of SARS-CoV-2 genomic surveillance in India during low positivity rate scenario
title_full Challenges of SARS-CoV-2 genomic surveillance in India during low positivity rate scenario
title_fullStr Challenges of SARS-CoV-2 genomic surveillance in India during low positivity rate scenario
title_full_unstemmed Challenges of SARS-CoV-2 genomic surveillance in India during low positivity rate scenario
title_short Challenges of SARS-CoV-2 genomic surveillance in India during low positivity rate scenario
title_sort challenges of sars-cov-2 genomic surveillance in india during low positivity rate scenario
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335399/
https://www.ncbi.nlm.nih.gov/pubmed/37441634
http://dx.doi.org/10.3389/fpubh.2023.1117602
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