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Diagnostic performance of the EU TI‐RADS and ACR TI‐RADS scoring systems in predicting thyroid malignancy
INTRODUCTION: Several ultrasound scoring systems have been developed to stratify the risk of malignancy of thyroid nodules, including ACR (American College of Radiology) and EU (European) TI‐RADS. This study aimed to assess the diagnostic performance of these two classifications using histology as a...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335610/ https://www.ncbi.nlm.nih.gov/pubmed/37327183 http://dx.doi.org/10.1002/edm2.434 |
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author | Chatti, Hiba‐Allah Oueslati, Ibtissem Azaiez, Aymen Marrakchi, Jihen Boukriba, Seif Mizouni, Habiba Haouet, Slim Besbes, Ghazi Yazidi, Meriem Chihaoui, Melika |
author_facet | Chatti, Hiba‐Allah Oueslati, Ibtissem Azaiez, Aymen Marrakchi, Jihen Boukriba, Seif Mizouni, Habiba Haouet, Slim Besbes, Ghazi Yazidi, Meriem Chihaoui, Melika |
author_sort | Chatti, Hiba‐Allah |
collection | PubMed |
description | INTRODUCTION: Several ultrasound scoring systems have been developed to stratify the risk of malignancy of thyroid nodules, including ACR (American College of Radiology) and EU (European) TI‐RADS. This study aimed to assess the diagnostic performance of these two classifications using histology as a reference standard. METHODS: It was a single‐centre, retrospective study including 156 patients who underwent thyroidectomy. Ultrasound data of 198 nodules (99 malignant nodules and 99 benign nodules) were analysed. Both classifications were applied for all nodules. RESULTS: Ultrasound criteria associated with malignancy were solid composition (OR=7.81; p < 10(−3)), hypoechoic character (OR=16.42; p < 10(−3)), irregular contours (OR=7.47; p < 10(−3)), taller‐than‐wide shape (OR=3.58; p = 0.02), microcalcifications (OR=3.02; p = .006) and the presence of cervical adenopathy (OR=3.89; p = .006). The prevalence of malignancy was 15.5%, 69% and 76.9% for EU TI‐RADS categories 3, 4 and 5, respectively. It was 33.3%, 57% and 91.1% for ACR TI‐RADS categories 3, 4 and 5, respectively. For category 5, EU TI‐RADS and ACR TI‐RADS had sensitivities of 60% and 41%, specificities of 82% and 96%, respectively. For categories 4 and 5 combined, the diagnostic performance of these two classification systems became comparable with a sensitivity of 89% and 86% for EU‐TIRADS and ACR‐TIRADS, respectively. The area under the ROC curve was 0.81 for the EU TI‐RADS classification and 0.82 for the ACR TI‐RADS classification. CONCLUSIONS: EU TI‐RADS and ACR TI‐RADS scoring systems seem to be comparable in predicting malignancy in thyroid nodules. |
format | Online Article Text |
id | pubmed-10335610 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-103356102023-07-12 Diagnostic performance of the EU TI‐RADS and ACR TI‐RADS scoring systems in predicting thyroid malignancy Chatti, Hiba‐Allah Oueslati, Ibtissem Azaiez, Aymen Marrakchi, Jihen Boukriba, Seif Mizouni, Habiba Haouet, Slim Besbes, Ghazi Yazidi, Meriem Chihaoui, Melika Endocrinol Diabetes Metab Research Articles INTRODUCTION: Several ultrasound scoring systems have been developed to stratify the risk of malignancy of thyroid nodules, including ACR (American College of Radiology) and EU (European) TI‐RADS. This study aimed to assess the diagnostic performance of these two classifications using histology as a reference standard. METHODS: It was a single‐centre, retrospective study including 156 patients who underwent thyroidectomy. Ultrasound data of 198 nodules (99 malignant nodules and 99 benign nodules) were analysed. Both classifications were applied for all nodules. RESULTS: Ultrasound criteria associated with malignancy were solid composition (OR=7.81; p < 10(−3)), hypoechoic character (OR=16.42; p < 10(−3)), irregular contours (OR=7.47; p < 10(−3)), taller‐than‐wide shape (OR=3.58; p = 0.02), microcalcifications (OR=3.02; p = .006) and the presence of cervical adenopathy (OR=3.89; p = .006). The prevalence of malignancy was 15.5%, 69% and 76.9% for EU TI‐RADS categories 3, 4 and 5, respectively. It was 33.3%, 57% and 91.1% for ACR TI‐RADS categories 3, 4 and 5, respectively. For category 5, EU TI‐RADS and ACR TI‐RADS had sensitivities of 60% and 41%, specificities of 82% and 96%, respectively. For categories 4 and 5 combined, the diagnostic performance of these two classification systems became comparable with a sensitivity of 89% and 86% for EU‐TIRADS and ACR‐TIRADS, respectively. The area under the ROC curve was 0.81 for the EU TI‐RADS classification and 0.82 for the ACR TI‐RADS classification. CONCLUSIONS: EU TI‐RADS and ACR TI‐RADS scoring systems seem to be comparable in predicting malignancy in thyroid nodules. John Wiley and Sons Inc. 2023-06-16 /pmc/articles/PMC10335610/ /pubmed/37327183 http://dx.doi.org/10.1002/edm2.434 Text en © 2023 The Authors. Endocrinology, Diabetes & Metabolism published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Articles Chatti, Hiba‐Allah Oueslati, Ibtissem Azaiez, Aymen Marrakchi, Jihen Boukriba, Seif Mizouni, Habiba Haouet, Slim Besbes, Ghazi Yazidi, Meriem Chihaoui, Melika Diagnostic performance of the EU TI‐RADS and ACR TI‐RADS scoring systems in predicting thyroid malignancy |
title | Diagnostic performance of the EU TI‐RADS and ACR TI‐RADS scoring systems in predicting thyroid malignancy |
title_full | Diagnostic performance of the EU TI‐RADS and ACR TI‐RADS scoring systems in predicting thyroid malignancy |
title_fullStr | Diagnostic performance of the EU TI‐RADS and ACR TI‐RADS scoring systems in predicting thyroid malignancy |
title_full_unstemmed | Diagnostic performance of the EU TI‐RADS and ACR TI‐RADS scoring systems in predicting thyroid malignancy |
title_short | Diagnostic performance of the EU TI‐RADS and ACR TI‐RADS scoring systems in predicting thyroid malignancy |
title_sort | diagnostic performance of the eu ti‐rads and acr ti‐rads scoring systems in predicting thyroid malignancy |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335610/ https://www.ncbi.nlm.nih.gov/pubmed/37327183 http://dx.doi.org/10.1002/edm2.434 |
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