Genital ulcers following all-trans-retinoic acid therapy: A case series with review of literature

All-trans-retinoic acid (ATRA) has transformed the treatment of acute promyelocytic leukemia. Most of the adverse effects associated with this drug are minor barring differentiation syndromes. Genital ulcers feature among the underreported adverse effects of ATRA which needs to be kept in mind to av...

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Autores principales: Saraswat, Neerja, Kumar, Sushil, Prem, Rahul, Tripathi, Durga Madhab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335649/
https://www.ncbi.nlm.nih.gov/pubmed/37313940
http://dx.doi.org/10.4103/ijp.ijp_811_21
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author Saraswat, Neerja
Kumar, Sushil
Prem, Rahul
Tripathi, Durga Madhab
author_facet Saraswat, Neerja
Kumar, Sushil
Prem, Rahul
Tripathi, Durga Madhab
author_sort Saraswat, Neerja
collection PubMed
description All-trans-retinoic acid (ATRA) has transformed the treatment of acute promyelocytic leukemia. Most of the adverse effects associated with this drug are minor barring differentiation syndromes. Genital ulcers feature among the underreported adverse effects of ATRA which needs to be kept in mind to avoid life-threatening complications. We describe two cases who developed genital ulcers while treated with ATRA.
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spelling pubmed-103356492023-07-12 Genital ulcers following all-trans-retinoic acid therapy: A case series with review of literature Saraswat, Neerja Kumar, Sushil Prem, Rahul Tripathi, Durga Madhab Indian J Pharmacol Drug Watch All-trans-retinoic acid (ATRA) has transformed the treatment of acute promyelocytic leukemia. Most of the adverse effects associated with this drug are minor barring differentiation syndromes. Genital ulcers feature among the underreported adverse effects of ATRA which needs to be kept in mind to avoid life-threatening complications. We describe two cases who developed genital ulcers while treated with ATRA. Wolters Kluwer - Medknow 2023 2023-06-03 /pmc/articles/PMC10335649/ /pubmed/37313940 http://dx.doi.org/10.4103/ijp.ijp_811_21 Text en Copyright: © 2023 Indian Journal of Pharmacology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Drug Watch
Saraswat, Neerja
Kumar, Sushil
Prem, Rahul
Tripathi, Durga Madhab
Genital ulcers following all-trans-retinoic acid therapy: A case series with review of literature
title Genital ulcers following all-trans-retinoic acid therapy: A case series with review of literature
title_full Genital ulcers following all-trans-retinoic acid therapy: A case series with review of literature
title_fullStr Genital ulcers following all-trans-retinoic acid therapy: A case series with review of literature
title_full_unstemmed Genital ulcers following all-trans-retinoic acid therapy: A case series with review of literature
title_short Genital ulcers following all-trans-retinoic acid therapy: A case series with review of literature
title_sort genital ulcers following all-trans-retinoic acid therapy: a case series with review of literature
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335649/
https://www.ncbi.nlm.nih.gov/pubmed/37313940
http://dx.doi.org/10.4103/ijp.ijp_811_21
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AT premrahul genitalulcersfollowingalltransretinoicacidtherapyacaseserieswithreviewofliterature
AT tripathidurgamadhab genitalulcersfollowingalltransretinoicacidtherapyacaseserieswithreviewofliterature

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