Isoforms of the TAL1 transcription factor have different roles in hematopoiesis and cell growth

T-cell acute lymphoblastic leukemia (T-ALL) protein 1 (TAL1) is a central transcription factor in hematopoiesis. The timing and level of TAL1 expression orchestrate the differentiation to specialized blood cells and its overexpression is a common cause of T-ALL. Here, we studied the 2 protein isofor...

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Detalles Bibliográficos
Autores principales: Sharma, Aveksha, Mistriel-Zerbib, Shani, Najar, Rauf Ahmad, Engal, Eden, Bentata, Mercedes, Taqatqa, Nadeen, Dahan, Sara, Cohen, Klil, Jaffe-Herman, Shiri, Geminder, Ophir, Baker, Mai, Nevo, Yuval, Plaschkes, Inbar, Kay, Gillian, Drier, Yotam, Berger, Michael, Salton, Maayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335695/
https://www.ncbi.nlm.nih.gov/pubmed/37379322
http://dx.doi.org/10.1371/journal.pbio.3002175

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