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Activation of aldehyde dehydrogenase-2 improves ischemic random skin flap survival in rats
OBJECTIVE: Random skin flaps have many applications in plastic and reconstructive surgeries. However, distal flap necrosis restricts wider clinical utility. Mitophagy, a vital form of autophagy for damaged mitochondria, is excessively activated in flap ischemia/reperfusion (I/R) injury, thus inducin...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335790/ https://www.ncbi.nlm.nih.gov/pubmed/37441072 http://dx.doi.org/10.3389/fimmu.2023.1127610 |