Cargando…
Transcriptomic classes of BCR-ABL1 lymphoblastic leukemia
In BCR-ABL1 lymphoblastic leukemia, treatment heterogeneity to tyrosine kinase inhibitors (TKIs), especially in the absence of kinase domain mutations in BCR-ABL1, is poorly understood. Through deep molecular profiling, we uncovered three transcriptomic subtypes of BCR-ABL1 lymphoblastic leukemia, e...
Autores principales: | Kim, Jaeseung C., Chan-Seng-Yue, Michelle, Ge, Sabrina, Zeng, Andy G. X., Ng, Karen, Gan, Olga I., Garcia-Prat, Laura, Flores-Figueroa, Eugenia, Woo, Tristan, Zhang, Amy Xin Wei, Arruda, Andrea, Chithambaram, Shivapriya, Dobson, Stephanie M., Khoo, Amanda, Khan, Shahbaz, Ibrahimova, Narmin, George, Ann, Tierens, Anne, Hitzler, Johann, Kislinger, Thomas, Dick, John E., McPherson, John D., Minden, Mark D., Notta, Faiyaz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335939/ https://www.ncbi.nlm.nih.gov/pubmed/37337105 http://dx.doi.org/10.1038/s41588-023-01429-4 |
Ejemplares similares
-
Differential Codon Adaptation between dsDNA and ssDNA Phages in Escherichia coli
por: Chithambaram, Shivapriya, et al.
Publicado: (2014) -
The Effect of Mutation and Selection on Codon Adaptation in Escherichia coli Bacteriophage
por: Chithambaram, Shivapriya, et al.
Publicado: (2014) -
Escherichia coli and Staphylococcus phages: effect of translation initiation efficiency on differential codon adaptation mediated by virulent and temperate lifestyles
por: Prabhakaran, Ramanandan, et al.
Publicado: (2015) -
Cryptic genomic lesions in adverse-risk acute myeloid leukemia identified by integrated whole genome and transcriptome sequencing
por: Kim, Jaeseung C., et al.
Publicado: (2019) -
Allosteric inhibition enhances the efficacy of ABL kinase inhibitors to target unmutated BCR-ABL and BCR-ABL-T315I
por: Mian, Afsar Ali, et al.
Publicado: (2012)