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Hypoxia-reprogramed megamitochondrion contacts and engulfs lysosome to mediate mitochondrial self-digestion

Mitochondria are the key organelles for sensing oxygen, which is consumed by oxidative phosphorylation to generate ATP. Lysosomes contain hydrolytic enzymes that degrade misfolded proteins and damaged organelles to maintain cellular homeostasis. Mitochondria physically and functionally interact with...

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Detalles Bibliográficos
Autores principales:	Hao, Tianshu, Yu, Jianglong, Wu, Zhida, Jiang, Jie, Gong, Longlong, Wang, Bingjun, Guo, Hanze, Zhao, Huabin, Lu, Bin, Engelender, Simone, He, He, Song, Zhiyin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336010/ https://www.ncbi.nlm.nih.gov/pubmed/37433770 http://dx.doi.org/10.1038/s41467-023-39811-9

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