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Deep learning identifies a T-cell exhaustion-dependent transcriptional signature for predicting clinical outcomes and response to immune checkpoint blockade

Immune checkpoint blockade (ICB) therapies have brought unprecedented advances in cancer treatment, but responses are limited to a fraction of patients. Therefore, sustained and substantial efforts are required to advance clinical and translational investigation on managing patients receiving ICB. I...

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Detalles Bibliográficos
Autores principales:	Zhang, Zicheng, Chen, Hongyan, Yan, Dongxue, Chen, Lu, Sun, Jie, Zhou, Meng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336094/ https://www.ncbi.nlm.nih.gov/pubmed/37433793 http://dx.doi.org/10.1038/s41389-023-00482-2

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