Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice

In Parkinson’s disease (PD), motor dysfunctions only become apparent after extensive loss of DA innervation. This resilience has been hypothesized to be due to the ability of many motor behaviors to be sustained through a diffuse basal tone of DA; but experimental evidence for this is limited. Here...

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Detalles Bibliográficos
Autores principales: Delignat-Lavaud, Benoît, Kano, Jana, Ducrot, Charles, Massé, Ian, Mukherjee, Sriparna, Giguère, Nicolas, Moquin, Luc, Lévesque, Catherine, Burke, Samuel, Denis, Raphaëlle, Bourque, Marie-Josée, Tchung, Alex, Rosa-Neto, Pedro, Lévesque, Daniel, De Beaumont, Louis, Trudeau, Louis-Éric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336101/
https://www.ncbi.nlm.nih.gov/pubmed/37433762
http://dx.doi.org/10.1038/s41467-023-39805-7

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