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Abatacept to induce remission of peanut allergy during oral immunotherapy (ATARI): protocol for a phase 2a randomized controlled trial

CONTEXT: While oral immunotherapy (OIT) has been shown to promote the remission of mild peanut allergy in young children, there is still an unmet need for a disease-modifying intervention for older patients and those with severe diseases. In mice models, abatacept, a cytotoxic T lymphocyte-associate...

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Detalles Bibliográficos
Autores principales: Braun, Camille, Azzano, Pauline, Gingras-Lessard, Florence, Roy, Émilie, Samaan, Kathryn, Graham, François, Paradis, Louis, Des Roches, Anne, Bégin, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336224/
https://www.ncbi.nlm.nih.gov/pubmed/37448803
http://dx.doi.org/10.3389/fmed.2023.1198173