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FOXP1 regulates oxidative stress, SIRT1 expression, and resistance to chemotherapies in acute myeloid leukemia cells

Transcription factor Forkhead box P1 (FOXP1) belongs to the same protein family as the FOXOs that are well-known regulators of murine hematopoietic stem progenitor cell (HSPC) maintenance via dampening oxidative stress. FOXP1 and FOXOs can play opposite, or similar, roles depending on cell context;...

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Detalles Bibliográficos
Autores principales: Levavasseur, Francoise, Oussous, Samia, Zubaidan, Tuerdi, Kosmider, Olivier, Pendino, Frédéric, Rombaut, David, Bouscary, Didier, Fontenay, Michaela, Lauret, Evelyne, Dusanter-Fourt, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336262/
https://www.ncbi.nlm.nih.gov/pubmed/36930820
http://dx.doi.org/10.1182/bloodadvances.2022008585