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Gata1s mutant mice display persistent defects in the erythroid lineage
GATA1 mutations that result in loss of the N-terminal 83 amino acids are a feature of myeloid leukemia in children with Down syndrome, rare familial cases of dyserythropoietic anemia, and a subset of cases of Diamond-Blackfan anemia. The Gata1s mouse model, which expresses only the short GATA1 isofo...
Autores principales: | Ling, Te, Zhang, Kevin, Yang, Jiayue, Gurbuxani, Sandeep, Crispino, John D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336263/ https://www.ncbi.nlm.nih.gov/pubmed/36350717 http://dx.doi.org/10.1182/bloodadvances.2022008124 |
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