Cargando…

Gata1s mutant mice display persistent defects in the erythroid lineage

GATA1 mutations that result in loss of the N-terminal 83 amino acids are a feature of myeloid leukemia in children with Down syndrome, rare familial cases of dyserythropoietic anemia, and a subset of cases of Diamond-Blackfan anemia. The Gata1s mouse model, which expresses only the short GATA1 isofo...

Descripción completa

Detalles Bibliográficos
Autores principales: Ling, Te, Zhang, Kevin, Yang, Jiayue, Gurbuxani, Sandeep, Crispino, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336263/
https://www.ncbi.nlm.nih.gov/pubmed/36350717
http://dx.doi.org/10.1182/bloodadvances.2022008124

Ejemplares similares