Inhibition of bacterial adhesion and anti-biofilm effects of Bacillus cereus and Serratia nematodiphila biosurfactants against Staphylococcus aureus and Pseudomonas aeruginosa

BACKGROUND AND OBJECTIVES: Biosurfactants are amphiphilic surface-active agents that mainly produced by various microorganisms. In this study, the anti-biofilm and inhibition of bacterial adhesion activities of two bacterial biosurfactants were investigated. MATERIALS AND METHODS: After extraction a...

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Detalles Bibliográficos
Autores principales: Keyhanian, Alireza, Mohammadimehr, Mojgan, Nojoomi, Farshad, Naghoosi, Hamed, Khomartash, Mehdi Shakouri, Chamanara, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336295/
https://www.ncbi.nlm.nih.gov/pubmed/37448686
http://dx.doi.org/10.18502/ijm.v15i3.12903
Descripción
Sumario:BACKGROUND AND OBJECTIVES: Biosurfactants are amphiphilic surface-active agents that mainly produced by various microorganisms. In this study, the anti-biofilm and inhibition of bacterial adhesion activities of two bacterial biosurfactants were investigated. MATERIALS AND METHODS: After extraction and evaluation of Bacillus cereus and Serratia nematodiphila biosurfctants, inhibition of bacterial adhesion and anti-biofilm effects of them on Staphylococcus aureus and Pseudomonas aeruginosa were determined. RESULTS: On average, the synergistic effect of two bacterial biosurfactants, caused about 60% decrease in adhesion and about 80% decrease in biofilm formation of S. aureus and P. aeruginosa. CONCLUSION: The results of this study showed that combination of B. cereus and S. nematodiphila biosurfactants would increase the potential of attachment inhibition and biofilm eradication with very low toxicity.

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