Cargando…
Unleashing NK- and CD8 T cells by combining monalizumab and trastuzumab for metastatic HER2-positive breast cancer: Results of the MIMOSA trial
The large majority of patients with HER2-positive metastatic breast cancer (MBC) will eventually develop resistance to anti-HER2 therapy and die of this disease. Despite, relatively high levels of stromal tumor infiltrating lymphocytes (sTILs), PD1-blockade has only shown modest responses. Monalizum...
Autores principales: | Geurts, V.C.M., Voorwerk, L., Balduzzi, S., Salgado, R., Van de Vijver, K., van Dongen, M.G.J., Kemper, I., Mandjes, I.A.M., Heuver, M., Sparreboom, W., Haanen, J.B.A.G., Sonke, G.S., Horlings, H.M., Kok, M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336326/ https://www.ncbi.nlm.nih.gov/pubmed/37393645 http://dx.doi.org/10.1016/j.breast.2023.06.007 |
Ejemplares similares
-
Monalizumab: inhibiting the novel immune checkpoint NKG2A
por: van Hall, Thorbald, et al.
Publicado: (2019) -
Immune landscape of breast tumors with low and intermediate estrogen receptor expression
por: Voorwerk, Leonie, et al.
Publicado: (2023) -
Learning in Plants: Lessons from Mimosa pudica
por: Abramson, Charles I., et al.
Publicado: (2016) -
An Electrometric Study of Mimosa
por: Burr, H. S.
Publicado: (1943) -
PD-L1 blockade in combination with carboplatin as immune induction in metastatic lobular breast cancer: the GELATO trial
por: Voorwerk, Leonie, et al.
Publicado: (2023)