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Metastatic melanoma presenting as rapidly enlarging hepatic cysts

Malignant melanoma is a highly aggressive disease with a propensity for metastatic spread. Although recent advances in targeted therapies have improved outcomes, effective screening for metastasis remains an important area of further research. We present a case of a man in his 70s who was recently d...

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Autores principales: Song, Christopher I., Buchanan, Mary Elizabeth, Maleki, Zahra, Gomez, Erin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336356/
https://www.ncbi.nlm.nih.gov/pubmed/37448605
http://dx.doi.org/10.1016/j.radcr.2023.06.031
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author Song, Christopher I.
Buchanan, Mary Elizabeth
Maleki, Zahra
Gomez, Erin
author_facet Song, Christopher I.
Buchanan, Mary Elizabeth
Maleki, Zahra
Gomez, Erin
author_sort Song, Christopher I.
collection PubMed
description Malignant melanoma is a highly aggressive disease with a propensity for metastatic spread. Although recent advances in targeted therapies have improved outcomes, effective screening for metastasis remains an important area of further research. We present a case of a man in his 70s who was recently diagnosed with recurrent, locally advanced melanoma. He presented with abdominal fullness, jaundice, and poor appetite. MR imaging of the abdomen revealed innumerable hepatic cysts with internal fluid-fluid levels which were markedly increased in size and number from recent imaging. These findings necessitated a broad differential that included parasitic or bacterial infection, metastases, or drug-induced polycystic liver disease. Subsequent biopsy revealed metastatic melanoma consistent with the patient's primary tumor. The patient was ultimately transitioned to comfort care measures due to the burden of the liver metastases and passed away shortly after presentation.
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spelling pubmed-103363562023-07-13 Metastatic melanoma presenting as rapidly enlarging hepatic cysts Song, Christopher I. Buchanan, Mary Elizabeth Maleki, Zahra Gomez, Erin Radiol Case Rep Case Report Malignant melanoma is a highly aggressive disease with a propensity for metastatic spread. Although recent advances in targeted therapies have improved outcomes, effective screening for metastasis remains an important area of further research. We present a case of a man in his 70s who was recently diagnosed with recurrent, locally advanced melanoma. He presented with abdominal fullness, jaundice, and poor appetite. MR imaging of the abdomen revealed innumerable hepatic cysts with internal fluid-fluid levels which were markedly increased in size and number from recent imaging. These findings necessitated a broad differential that included parasitic or bacterial infection, metastases, or drug-induced polycystic liver disease. Subsequent biopsy revealed metastatic melanoma consistent with the patient's primary tumor. The patient was ultimately transitioned to comfort care measures due to the burden of the liver metastases and passed away shortly after presentation. Elsevier 2023-07-01 /pmc/articles/PMC10336356/ /pubmed/37448605 http://dx.doi.org/10.1016/j.radcr.2023.06.031 Text en © 2023 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Song, Christopher I.
Buchanan, Mary Elizabeth
Maleki, Zahra
Gomez, Erin
Metastatic melanoma presenting as rapidly enlarging hepatic cysts
title Metastatic melanoma presenting as rapidly enlarging hepatic cysts
title_full Metastatic melanoma presenting as rapidly enlarging hepatic cysts
title_fullStr Metastatic melanoma presenting as rapidly enlarging hepatic cysts
title_full_unstemmed Metastatic melanoma presenting as rapidly enlarging hepatic cysts
title_short Metastatic melanoma presenting as rapidly enlarging hepatic cysts
title_sort metastatic melanoma presenting as rapidly enlarging hepatic cysts
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336356/
https://www.ncbi.nlm.nih.gov/pubmed/37448605
http://dx.doi.org/10.1016/j.radcr.2023.06.031
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