Escaping but not the inactive X-linked protein complex coding genes may achieve X-chromosome dosage compensation and underlie X chromosome inactivation-related diseases

X chromosome dosage compensation (XDC) refers to the process by which X-linked genes acquire expression equivalence between two sexes. Ohno proposed that XDC is achieved by two-fold upregulations of X-linked genes in both sexes and by silencing one X chromosome (X chromosome inactivation, XCI) in fe...

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Detalles Bibliográficos
Autores principales: Xing, Zhihao, Zhang, Yuchao, Tian, Zhongyuan, Wang, Meng, Xiao, Weiwei, Zhu, Chunqing, Zhao, Songhui, Zhu, Yufei, Hu, Landian, Kong, Xiangyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336589/
https://www.ncbi.nlm.nih.gov/pubmed/37449161
http://dx.doi.org/10.1016/j.heliyon.2023.e17721

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