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The association between visceral adiposity index and chronic kidney disease in the elderly: A cross-sectional analysis of NHANES 2011–2018
Visceral adiposity index (VAI) is a new metric for evaluating visceral adiposity dysfunction. The aim of the present study was to explore the association between VAI and incident chronic kidney disease (CKD) in the American elderly population. We included 6085 participants aged 60 years or older wit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336672/ https://www.ncbi.nlm.nih.gov/pubmed/37449005 http://dx.doi.org/10.1016/j.pmedr.2023.102306 |
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author | Peng, Wei Han, Min Xu, Gang |
author_facet | Peng, Wei Han, Min Xu, Gang |
author_sort | Peng, Wei |
collection | PubMed |
description | Visceral adiposity index (VAI) is a new metric for evaluating visceral adiposity dysfunction. The aim of the present study was to explore the association between VAI and incident chronic kidney disease (CKD) in the American elderly population. We included 6085 participants aged 60 years or older with available data on renal function and VAI from the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2018 and divided them into four groups according to the VAI quartiles. VAI values were ln-transformed to reduce skewness. We conducted multivariable logistic regression analyses and spline smoothing plot analyses to evaluate the association between VAI and CKD. After fully adjusting for confounding factors, higher lnVAI was associated with a higher risk of CKD (OR, 1.23; 95 %CI, 1.02, 1.48). Compared to the Q1 group (VAI < 1.1), The third and fourth VAI quartiles were associated with a higher prevalence of CKD (Q3: VAI, 1.8–3.0; Q4: VAI > 3.0). The adjusted ORs (95% CI) in Q3 and Q4 were 1.74 (1.24, 2.42) and 1.59 (1.08, 2.33). Adjusted smoothed plots suggested a nonlinear relationship between lnVAI and CKD. The development of CKD increased with increasing VAI among participants with a lnVAI between −0.6 and 1.6 (VAI: 0.5–5.0). In conclusion, VAI is significantly associated with the risk of CKD in the US elderly population aged 60 years or older. |
format | Online Article Text |
id | pubmed-10336672 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
record_format | MEDLINE/PubMed |
spelling | pubmed-103366722023-07-13 The association between visceral adiposity index and chronic kidney disease in the elderly: A cross-sectional analysis of NHANES 2011–2018 Peng, Wei Han, Min Xu, Gang Prev Med Rep Regular Article Visceral adiposity index (VAI) is a new metric for evaluating visceral adiposity dysfunction. The aim of the present study was to explore the association between VAI and incident chronic kidney disease (CKD) in the American elderly population. We included 6085 participants aged 60 years or older with available data on renal function and VAI from the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2018 and divided them into four groups according to the VAI quartiles. VAI values were ln-transformed to reduce skewness. We conducted multivariable logistic regression analyses and spline smoothing plot analyses to evaluate the association between VAI and CKD. After fully adjusting for confounding factors, higher lnVAI was associated with a higher risk of CKD (OR, 1.23; 95 %CI, 1.02, 1.48). Compared to the Q1 group (VAI < 1.1), The third and fourth VAI quartiles were associated with a higher prevalence of CKD (Q3: VAI, 1.8–3.0; Q4: VAI > 3.0). The adjusted ORs (95% CI) in Q3 and Q4 were 1.74 (1.24, 2.42) and 1.59 (1.08, 2.33). Adjusted smoothed plots suggested a nonlinear relationship between lnVAI and CKD. The development of CKD increased with increasing VAI among participants with a lnVAI between −0.6 and 1.6 (VAI: 0.5–5.0). In conclusion, VAI is significantly associated with the risk of CKD in the US elderly population aged 60 years or older. 2023-06-28 /pmc/articles/PMC10336672/ /pubmed/37449005 http://dx.doi.org/10.1016/j.pmedr.2023.102306 Text en © 2023 Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Regular Article Peng, Wei Han, Min Xu, Gang The association between visceral adiposity index and chronic kidney disease in the elderly: A cross-sectional analysis of NHANES 2011–2018 |
title | The association between visceral adiposity index and chronic kidney disease in the elderly: A cross-sectional analysis of NHANES 2011–2018 |
title_full | The association between visceral adiposity index and chronic kidney disease in the elderly: A cross-sectional analysis of NHANES 2011–2018 |
title_fullStr | The association between visceral adiposity index and chronic kidney disease in the elderly: A cross-sectional analysis of NHANES 2011–2018 |
title_full_unstemmed | The association between visceral adiposity index and chronic kidney disease in the elderly: A cross-sectional analysis of NHANES 2011–2018 |
title_short | The association between visceral adiposity index and chronic kidney disease in the elderly: A cross-sectional analysis of NHANES 2011–2018 |
title_sort | association between visceral adiposity index and chronic kidney disease in the elderly: a cross-sectional analysis of nhanes 2011–2018 |
topic | Regular Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336672/ https://www.ncbi.nlm.nih.gov/pubmed/37449005 http://dx.doi.org/10.1016/j.pmedr.2023.102306 |
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