Synoviolin alleviates GSDMD‐mediated periodontitis by suppressing its stability

INTRODUCTION: Inflammasome and pyroptosis play important roles in periodontitis. Gasdermin D (GSDMD), a key factor in pyroptosis, is cleaved by caspase‐1 and regulated by ubiquitination. Synoviolin is a ubiquitin E3 ligase that interacts with GSDMD. In this study, the effects of Synoviolin on inflam...

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Detalles Bibliográficos
Autores principales: Pang, Ying, Liu, Lili, Wu, Shuainan, Wang, Jianqi, Liu, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336677/
https://www.ncbi.nlm.nih.gov/pubmed/37506160
http://dx.doi.org/10.1002/iid3.880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336677/
https://www.ncbi.nlm.nih.gov/pubmed/37506160
http://dx.doi.org/10.1002/iid3.880

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